Moritani Toshio, Aihara Toshinori, Oguma Eiji, Makiyama Yasuhide, Nishimoto Hiroshi, Smoker Wendy R K, Sato Yutaka
Department of Radiology, Saitama Children's Medical Center, 2100 Magome, Iwatsuki, Saitama 339, Japan.
Clin Imaging. 2006 May-Jun;30(3):195-200. doi: 10.1016/j.clinimag.2005.10.004.
In achondroplasia, venous narrowing associated with a small skull base leads to elevated venous pressure which impairs cerebrospinal fluid (CSF) absorption, resulting in communicating hydrocephalus. We correlated venous narrowing at the jugular foramina and collateral circulation on magnetic resonance venography (MRV) with ventricular size in 17 patients. Patients were divided into three groups: Group I: progressive hydrocephalus; Group II: nonprogressive hydrocephalus; and Group III: normal ventricular size. The grades of venous narrowing and types of collaterals were well correlated with hydrocephalus groups.
在软骨发育不全中，与小颅底相关的静脉狭窄导致静脉压升高，这会损害脑脊液（CSF）的吸收，从而导致交通性脑积水。我们对17例患者磁共振静脉血管造影（MRV）上颈静脉孔处的静脉狭窄及侧支循环与脑室大小进行了相关性分析。患者被分为三组：第一组：进行性脑积水；第二组：非进行性脑积水；第三组：脑室大小正常。静脉狭窄程度和侧支类型与脑积水组显著相关。
