Faries Mark B
John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA.
Surg Oncol Clin N Am. 2006 Apr;15(2):399-418. doi: 10.1016/j.soc.2005.12.008.
These data show that the extraordinary potency of the immune system can be harnessed to control or destroy melanoma. The proven impact has been limited for patients who have melanoma, but has been dramatic and lasting in selected groups. Recent improvements in understanding of immunology, including mechanisms regulating immune responses and methods of tumor cell escape, are already yielding improved clinical outcomes and potential avenues for extending benefits to more patients. Thus, although the full potential of this treatment modality has yet to be realized, the vanguard of the "treatment of tomorrow" has clearly arrived.
这些数据表明，免疫系统的强大效力可被用于控制或摧毁黑色素瘤。对于黑色素瘤患者，已证实的影响有限，但在特定群体中却产生了显著且持久的效果。近期在免疫学理解方面的进展，包括调节免疫反应的机制以及肿瘤细胞逃逸的方法，已经带来了更好的临床结果，并且为将益处扩展至更多患者提供了潜在途径。因此，尽管这种治疗方式的全部潜力尚未实现，但“明日治疗”的先锋显然已经到来。
