肺淋巴上皮瘤样癌：一种罕见的原发性肺肿瘤的放射学特征
Lymphoepithelioma-like carcinoma of the lung: radiologic features of an uncommon primary pulmonary neoplasm.
作者信息
Hoxworth Joseph M, Hanks Douglas K, Araoz Philip A, Elicker Brett M, Reddy Gautham P, Webb W Richard, Leung Jessica W T, Gotway Michael B
机构信息
Department of Radiology, University of California, San Francisco, 505 Parnassus Avenue, Room M-391, Box 0628, San Francisco, CA 94110, USA.
出版信息
AJR Am J Roentgenol. 2006 May;186(5):1294-9. doi: 10.2214/AJR.05.0244.
OBJECTIVE
The purpose of this study was to review the chest radiographic, CT, and MRI appearances of primary pulmonary lymphoepithelioma-like carcinoma (LELC).
CONCLUSION
Primary pulmonary LELC is histopathologically identical to nasopharyngeal carcinoma. The radiographic, CT, and MRI features of primary pulmonary LELC are nonspecific, often resembling those of bronchogenic carcinoma. Primary pulmonary LELC usually presents as a poorly circumscribed, enhancing, peripheral solitary pulmonary nodule on CT; necrosis may be present and is considered a poor prognostic sign. MRI shows isointense to low-intensity signal on T1-weighted images and mildly increased signal on T2-weighted images; enhancement of abnormal tissue is typical. Most patients present with early-stage disease. Primary pulmonary LELC should be suspected in selected patients and requires differentiation from bronchogenic carcinoma and metastatic nasopharyngeal carcinoma.
目的
本研究旨在回顾原发性肺淋巴上皮瘤样癌（LELC）的胸部X线、CT及MRI表现。
结论
原发性肺LELC在组织病理学上与鼻咽癌相同。原发性肺LELC的X线、CT及MRI表现无特异性，常类似于支气管肺癌。原发性肺LELC在CT上通常表现为边界不清、强化的外周孤立性肺结节；可能存在坏死，这被认为是预后不良的征象。MRI在T1加权图像上显示等信号至低信号，在T2加权图像上信号轻度增加；异常组织强化是典型表现。大多数患者表现为疾病早期。对于特定患者应怀疑原发性肺LELC，且需要与支气管肺癌和转移性鼻咽癌相鉴别。
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