Priya Anshu, Spalgais Sonam, Kulshrestha Ritu, Kumar Raj
Department of Pulmonary Medicine, KEM Hospital, Mumbai, India.
Vallabhbhai Patel Chest Institute, Flat No 8 VPCI Flats, Maurice Nagar, Delhi, India.
Med J Armed Forces India. 2023 Mar-Apr;79(2):220-224. doi: 10.1016/j.mjafi.2021.08.006. Epub 2021 Oct 11.
Lymphoepithelial-like carcinoma (LELC) usually presents as a head and neck tumor with a close resemblance to nasopharyngeal carcinoma. We present an extremely rare case of Primary Pulmonary lymphoepithelioma in a 14-year-old female patient. The patient presented with a right-sided lung mass, which on biopsy revealed to be a lymphoepithelioma. There was no evidence of any mass elsewhere in the body, including the nasopharynx, as evidenced by PET CT. The IHC was positive for both cytokeratin and lymphoid cell markers. Hence, we conclude that lymphoepitheliomas can present as a primary lung mass in a young nonsmoking female, of which only two case reports are available from the Indian subcontinent till date.
淋巴上皮样癌(LELC)通常表现为头颈部肿瘤,与鼻咽癌极为相似。我们报告一例极为罕见的14岁女性原发性肺淋巴上皮瘤病例。该患者表现为右侧肺部肿块,活检显示为淋巴上皮瘤。正电子发射断层显像(PET CT)显示身体其他部位,包括鼻咽部,均未发现任何肿块迹象。免疫组化(IHC)显示细胞角蛋白和淋巴细胞标志物均呈阳性。因此,我们得出结论,淋巴上皮瘤可表现为年轻非吸烟女性的原发性肺部肿块,迄今为止,印度次大陆仅有两篇相关病例报告。