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主动脉手术中腹腔内二氧化碳充气时的心脏功能:一项经食管超声心动图研究

Cardiac function during intraperitoneal CO2 insufflation for aortic surgery: a transesophageal echocardiographic study.

作者信息

Alfonsi Pascal, Vieillard-Baron Antoine, Coggia Marc, Guignard Bruno, Goeau-Brissonniere Olivier, Jardin François, Chauvin Marcel

机构信息

Department of Anesthesiology, and Intensive Care Unit, Ambroise Paré University Hospital, Assistance Publique Hôpitaux de Paris, Boulogne, Cedex, France.

出版信息

Anesth Analg. 2006 May;102(5):1304-10. doi: 10.1213/01.ane.0000202473.17453.79.

Abstract

The effect of laparoscopy on cardiac function is controversial. We hypothesized that cardiac dysfunction related to increased afterload could be predominant in patients undergoing elective abdominal aortic repair. To test this hypothesis, we conducted a transesophageal echocardiographic study in 15 patients during laparoscopic aortic surgery. We systematically assessed left ventricular (LV) and right ventricular (RV) functions. Measurements were obtained in the supine position without pneumoperitoneum and with an intraabdominal pressure of 14 mm Hg. Then, patients were turned to the right lateral position without pneumoperitoneum and intraabdominal pressure was increased to 7 mm Hg and to 14 mm Hg. Pneumoperitoneum induced a 25% arterial blood pressure increase and a 38% increase in LV systolic wall stress. A 25% decrease in LV ejection fraction and an 18% decrease in LV stroke volume were observed, associated with an increase in LV end-systolic volume. LV diastolic function impairment was observed without change in LV end-diastolic volume. Respiratory alterations in superior vena cava diameter were never observed, suggesting that volume status remained optimal. Respiratory changes in RV stroke volume were increased according to intraabdominal pressure and body position, reflecting an increase in RV afterload. In conclusion, peritoneal CO2 insufflation in patients scheduled for laparoscopic aortic surgery could impair LV and RV systolic functions as a consequence of increased afterload.

摘要

腹腔镜检查对心脏功能的影响存在争议。我们推测,在接受择期腹主动脉修复术的患者中,与后负荷增加相关的心脏功能障碍可能占主导地位。为了验证这一假设,我们在15例接受腹腔镜主动脉手术的患者中进行了经食管超声心动图研究。我们系统地评估了左心室(LV)和右心室(RV)功能。在无气腹且腹腔内压力为14 mmHg的仰卧位进行测量。然后,患者转为右侧卧位,无气腹,腹腔内压力分别增加至7 mmHg和14 mmHg。气腹导致动脉血压升高25%,左心室收缩壁应力增加38%。观察到左心室射血分数降低25%,左心室每搏量降低18%,同时左心室收缩末期容积增加。观察到左心室舒张功能受损,但左心室舒张末期容积无变化。从未观察到上腔静脉直径的呼吸性改变,表明容量状态保持最佳。右心室每搏量的呼吸变化根据腹腔内压力和体位而增加,反映了右心室后负荷增加。总之,计划进行腹腔镜主动脉手术的患者进行腹膜二氧化碳充气可能会由于后负荷增加而损害左心室和右心室的收缩功能。

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