McCluggage W Glenn
Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland.
Int J Gynecol Pathol. 2006 Apr;25(2):101-20. doi: 10.1097/01.pgp.0000192269.14666.68.
There has been a marked expansion in the literature pertaining to the use of immunohistochemical markers in female genital tract pathology, especially with regard to diagnosis. This review provides a survey of the antibodies commonly used in the diagnosis of gynecological lesions grouped as to function or type. Prognostic or predictive markers are also discussed where appropriate, although few of these are of value in everyday practice. It is stressed that when immunohistochemistry is used diagnostically, panels of markers provide better information than reliance on a single antibody.
关于免疫组织化学标志物在女性生殖道病理学中的应用，尤其是在诊断方面的文献有了显著增加。本综述对按功能或类型分组的妇科病变诊断中常用的抗体进行了概述。在适当的情况下，还讨论了预后或预测标志物，尽管其中很少有在日常实践中有价值的。需要强调的是，当免疫组织化学用于诊断时，标志物组合比依赖单一抗体能提供更好的信息。
