Kiel Jeffrey W, Reitsamer Herbert A
Department of Ophthalmology, University of Texas Health Science Center, San Antonio, TX 78229, USA.
J Glaucoma. 2006 Apr;15(2):172-81. doi: 10.1097/00061198-200604000-00015.
This review will summarize the authors' recent studies of the relationship between ciliary blood flow and aqueous production, and discuss the relevance of that relationship to the mechanisms of action of glaucoma drugs that lower intraocular pressure by inhibiting aqueous production. The ciliary processes are not easily accessible, and so the data presented necessarily come from animals and from instrumentation operated at its engineering limits. Verification of the findings in humans, and perhaps refinement of the interpretations, must await future advances in technology. Nonetheless, the results to date are intriguing, and may help explain some paradoxes in glaucoma pharmacology.
本综述将总结作者近期关于睫状体血流与房水生成之间关系的研究，并讨论该关系与通过抑制房水生成来降低眼压的青光眼药物作用机制的相关性。睫状体不易触及，因此所呈现的数据必然来自动物以及在工程极限条件下操作的仪器。在人体中对这些发现进行验证以及或许对解释进行完善，必须等待未来技术的进步。尽管如此，迄今为止的结果很有趣，可能有助于解释青光眼药理学中的一些矛盾之处。
