Adeolu A A, Shokunbi M T, Malomo A O, Akang E A A, Obajimi M O, Komolafe E O
Department of Surgery, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, and University of Ibadan College Hospital, Nigeria.
Niger Postgrad Med J. 2006 Mar;13(1):69-72.
Poverty, drug resistance and the advent of human immunodeficiency virus infection (HIV) have led to a recent upsurge in the incidence of tuberculosis including intracranial tuberculosis. In this article, we report 3 patients who had solitary brain tuberculomas and were otherwise healthy to underscore the importance of continuing vigilance for this disease.
Three patients (57 years, female; 52 years, male; 7 years male) presented to our unit with features of intracranial tumours. They were all HIV negative with no previous history of tuberculosis. Cranial computed tomography scans demonstrated uniformly contrast enhancing falcine supratentorial masses in the adult patients and a cerebellar hemispheric lesion with peripheral contrast enhancement in the paediatric patient
All the patients had gross total tumour excision. The histology confirmed a tuberculoma. They all had antituberculous therapy after histological confirmation. The outcome was good in all the patients.
Intracranial tuberculoma can occur in otherwise healthy individuals and should always be considered in the differential diagnosis of solitary intracranial mass lesions in sub-Saharan Africans so that minimally invasive procedures can be used to establish the correct diagnosis.
贫困、耐药性以及人类免疫缺陷病毒感染（HIV）的出现导致包括颅内结核在内的结核病发病率近期有所上升。在本文中，我们报告了3例患有孤立性脑结核瘤且无其他健康问题的患者，以强调对该疾病持续保持警惕的重要性。
3例患者（57岁女性、52岁男性、7岁男性）因颅内肿瘤特征前来我院就诊。他们均为HIV阴性，既往无结核病史。头颅计算机断层扫描显示，成年患者有均匀强化的大脑镰幕上肿块，儿科患者有小脑半球病变且周边强化。
所有患者均接受了肿瘤全切手术。组织学检查确诊为结核瘤。组织学确诊后，他们均接受了抗结核治疗。所有患者预后良好。
颅内结核瘤可发生于无其他健康问题的个体，在撒哈拉以南非洲地区，对于孤立性颅内肿块病变的鉴别诊断中应始终考虑到该病，以便采用微创方法确立正确诊断。
