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它能降到多低?预测新西兰到2015年的缺血性心脏病死亡率。

How low can it go? Projecting ischaemic heart disease mortality in New Zealand to 2015.

作者信息

Tobias Martin, Sexton Kerry, Mann Stewart, Sharpe Norman

机构信息

Ministry of Health, Wellington.

出版信息

N Z Med J. 2006 Apr 21;119(1232):U1932.

PMID:16633391
Abstract

AIMS

This study aims to identify how ischaemic heart disease (IHD) mortality rates in New Zealand have varied between successive cohorts and time periods. This information is then used to project IHD mortality rates and counts (burdens) out to year 2011-15.

METHODS

Age/period/cohort models were constructed (5-year periods and 5-year age groups, generating 10-year overlapping cohorts) using both frequentist and Bayesian methods. Data were available from 1956 for the total population and from 1981 for Maori. The projection period was 2001-5 to 2011-15. Uncertainty was quantified as the Bayesian 90% credible interval.

RESULTS

IHD mortality rates for all age by gender groups increased from 1956-60 to peak in 1966-70, then declined by more than 60% to current (1996-2000) levels. However, the decline has been much shallower for Maori. This decline has resulted from increasingly favourable period effects since 1971-75 (less marked for Maori). However, no substantive cohort effects have been seen, at least from the 1891 to the 1951 cohort. Our model suggests that, for the first time, a substantive and unfavourable cohort effect may be emerging among recent birth cohorts.

CONCLUSIONS

IHD mortality rates are projected to continue to fall from 2001-05 to 2011-15, albeit more slowly than in the past as the increasing (favourable) period effect is partly offset by an emerging (unfavourable) cohort effect. The result is a relatively small projected decline in absolute IHD mortality burden overall, but an actual increase among Maori.

摘要

目的

本研究旨在确定新西兰缺血性心脏病(IHD)死亡率在连续队列和时间段之间是如何变化的。然后利用这些信息预测到2011 - 2015年期间的IHD死亡率和死亡人数(负担)。

方法

使用频率论和贝叶斯方法构建年龄/时期/队列模型(5年时间段和5岁年龄组,产生10年重叠队列)。可获得1956年以来总人口的数据以及1981年以来毛利人的数据。预测期为2001 - 2005年至2011 - 2015年。不确定性以贝叶斯90%可信区间进行量化。

结果

所有年龄性别组的IHD死亡率从1956 - 1960年上升,在1966 - 1970年达到峰值,然后下降超过60%至当前(1996 - 2000年)水平。然而,毛利人的下降幅度要小得多。这种下降是由于自1971 - 1975年以来时期效应越来越有利(毛利人不太明显)。然而,至少从1891年到1951年队列,没有观察到实质性的队列效应。我们的模型表明,首次可能在最近出生队列中出现实质性且不利的队列效应。

结论

预计IHD死亡率在2001 - 2005年至2011 - 2015年期间将继续下降,尽管比过去更慢,因为不断增加的(有利的)时期效应部分被新出现的(不利的)队列效应所抵消。结果是总体IHD绝对死亡负担预计下降幅度相对较小,但毛利人实际增加。

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