Huygen P E, Feenstra B W, Hoorn E, Jansen J R, Zwart A
Department of Surgery, University Hospital, Rotterdam, The Netherlands.
Comput Methods Programs Biomed. 1991 Dec;36(4):223-35. doi: 10.1016/0169-2607(91)90091-7.
A data acquisition and processing system for the analysis of inert gas wash-out tests is described. The described system is in clinical use on spontaneously breathing patients as well as on mechanically ventilated Intensive Care patients. It combines several analysis techniques with an aim to provide a deeper insight into the nature of existing ventilation inhomogeneity than the individual techniques alone can provide. The signals measured are the respiratory flow, the fractions of one or two indicator gases washing out and the fractions of the metabolic gases oxygen and carbon dioxide. Analysis of these signals provides information concerning the end-expiratory lung-volume, distribution of ventilation and perfusion in the lung, the role of diffusion in the ventilation process and the metabolic oxygen uptake and CO2 release. This article describes the algorithms used and the results that are presented.
描述了一种用于分析惰性气体洗脱试验的数据采集和处理系统。所描述的系统正在临床上用于自主呼吸患者以及机械通气的重症监护患者。它结合了多种分析技术，旨在比单独的个别技术更深入地洞察现有通气不均匀性的本质。所测量的信号包括呼吸流量、一种或两种指示气体的洗脱分数以及代谢气体氧气和二氧化碳的分数。对这些信号的分析提供了有关呼气末肺容积、肺内通气和灌注分布、扩散在通气过程中的作用以及代谢性氧气摄取和二氧化碳释放的信息。本文描述了所使用的算法以及所呈现的结果。
