Duchková H
Kozní oddilení--Masarykova nemocnice, Ustí nad Labem.
Cas Lek Cesk. 2006;145(3):189-94.
Female androgenetic alopecia belongs to the family of scar-less, diffuse, telogenic, hormonally determined alopecias with hereditary disposition. In the androgenetic alopecia, progressive, androgen mediated miniaturization of genetically predestined hair follicles develops. Genetic factors play a role namely in females without the higher serum androgen level. Pathologically high level of serum androgens is usually accompanied with signs of virilization. Hair dropping starts in the fourth decade or earlier. It occurs in the postmenopausal period, after a pregnancy, after the onset or termination of peroral contraception, in women treated by aromatase inhibitors.
女性雄激素性脱发属于无瘢痕、弥漫性、休止期、激素性脱发家族，具有遗传倾向。在雄激素性脱发中，遗传易感性毛囊会逐渐发生雄激素介导的小型化。遗传因素在血清雄激素水平不高的女性中起作用。病理性高血清雄激素水平通常伴有男性化体征。脱发始于40岁或更早。可发生在绝经后期、怀孕后、口服避孕药开始或停止后、接受芳香化酶抑制剂治疗的女性中。
