Hobson Howard Phil, Brown Marjorie Raquel, Rogers Kenita S
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843-4474, USA.
Vet Surg. 2006 Apr;35(3):267-70. doi: 10.1111/j.1532-950X.2006.00137.x.
To identify survival and morbidity information after surgery for metastases from apocrine gland anal sac adenocarcinomas (AGACA).
Retrospective study.
Five dogs with AGACA.
Medical records of dogs that had surgery for treatment of metastatic AGACA between 1993 and 2003 were reviewed. Criteria for inclusion required that dogs had lymphadenectomy, with or without further debulking, as part of their treatment for metastatic AGACA and that the tissue was histologically confirmed as consistent with the primary AGACA. Signalment, history, physical examination findings, clinicopathologic data, imaging findings, surgical complications, number of surgeries, survival times, and cause of death were recorded. All dogs had a complete blood count, serum biochemical profile, serum electrolytes, 3-projection thoracic radiographs, abdominal radiographs and/or abdominal ultrasonography, and histologic confirmation of metastatic AGACA invading the regional lymph nodes and caudal abdomen.
No surgical complications occurred. Three dogs were euthanatized; median survival, 20.6 months. One dog was alive for 19 months postoperatively. One dog had 5 sequential surgical procedures: 1 iliac lymphadenectomy and 4 debulking procedures of metastatic neoplastic tissue around and dorsal to the iliac vessels extending into the pelvic cavity, and was alive 54 months after initial surgery.
Dogs with anal sac adenocarcinoma metastases to the iliac lymph nodes can experience long-term survival after surgical excision of the metastatic lesion.
Lymphadenectomy may afford long-term survival to patients with metastatic anal sac adenocarcinoma.
确定大汗腺肛门囊腺癌（AGACA）转移灶手术后的生存及发病信息。
回顾性研究。
5只患有AGACA的犬。
回顾1993年至2003年间因转移性AGACA接受手术治疗的犬的病历。纳入标准要求犬作为转移性AGACA治疗的一部分接受了淋巴结切除术，无论是否进行进一步的肿瘤减积手术，且组织经组织学证实与原发性AGACA一致。记录品种、病史、体格检查结果、临床病理数据、影像学检查结果、手术并发症、手术次数、生存时间和死亡原因。所有犬均进行了全血细胞计数、血清生化指标检测、血清电解质检测、胸部3投影X线片、腹部X线片和/或腹部超声检查，以及转移性AGACA侵犯区域淋巴结和尾腹部的组织学证实。
未发生手术并发症。3只犬实施了安乐死；中位生存期为20.6个月。1只犬术后存活了19个月。1只犬连续接受了5次手术：1次髂淋巴结切除术和4次对髂血管周围及背侧延伸至盆腔的转移性肿瘤组织进行的肿瘤减积手术，初次手术后存活了54个月。
患有肛门囊腺癌转移至髂淋巴结的犬在手术切除转移病灶后可实现长期存活。
淋巴结切除术可能为转移性肛门囊腺癌患者带来长期生存。
