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胸壁多灶性间叶性错构瘤

Multifocal mesenchymal hamartoma of the chest wall.

作者信息

Altaner Semsi, Yoruk Yener, Bilgi Selcuk, Puyan Fulya Oz, Doganay Latife, Kutlu Kemal

机构信息

Department of Pathology, Trakya University Medical Faculty, Edirne, Turkey.

出版信息

Respirology. 2006 May;11(3):334-8. doi: 10.1111/j.1440-1843.2006.00853.x.

DOI:10.1111/j.1440-1843.2006.00853.x
PMID:16635095
Abstract

Chest wall hamartomas are extremely rare. Frequently mesenchymal hamartomas are presented as a single mass and contain some primitive mesenchymal elements such as chondroid and trabecular bone structures. A 60-year-old man presented to hospital with chest pain. Thirteen years earlier, his CXR and thoracic CT showed three masses on the right and two masses on the left, but he had not received any treatment thereafter. His CT showed the same masses present 13 years earlier, but they were bigger and right thoracotomy was undertaken. At thoracotomy, two sections of the mass in the right posterior mediastinum and one section of the mass in the right apex were excised. They had an occasional bloody appearance and contained small cystic areas, and some areas were extremely hard. Microscopic examination showed that the lesions consisted of mature adipose tissue, a large number of veins of different diameters and collagen tissue. Besides, primitive mesenchymal elements, lymphoid cell accumulations and trabecular bone structures were seen focally. Bilateral chest wall hamartomas are extremely rare and may be confused with malignancy.

摘要

胸壁错构瘤极为罕见。间叶性错构瘤常表现为单个肿块,包含一些原始间叶成分,如软骨样和小梁状骨结构。一名60岁男性因胸痛入院。13年前,他的胸部X光片和胸部CT显示右侧有3个肿块,左侧有2个肿块,但此后他未接受任何治疗。他的CT显示与13年前相同的肿块,但肿块更大了,于是进行了右胸切开术。在开胸手术中,切除了右后纵隔肿块的两部分和右肺尖肿块的一部分。它们偶尔呈血性外观,含有小囊性区域,有些区域非常坚硬。显微镜检查显示,病变由成熟脂肪组织、大量不同直径的静脉和胶原组织组成。此外,局部可见原始间叶成分、淋巴细胞聚集和小梁状骨结构。双侧胸壁错构瘤极为罕见,可能会与恶性肿瘤混淆。

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