添加二十二碳六烯酸（DHA）和花生四烯酸（ARA）的配方奶粉：研究的批判性综述
Formula supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA): a critical review of the research.
作者信息
Wright Kristen, Coverston Catherine, Tiedeman Mary, Abegglen Jo Ann
机构信息
Brigham Young University-Nursing, Provo, UT, USA.
出版信息
J Spec Pediatr Nurs. 2006 Apr;11(2):100-12; discussion 112-3. doi: 10.1111/j.1744-6155.2006.00048.x.
PURPOSE
To summarize results of randomized controlled trials (RCTs) evaluating growth, cognitive, neurological, and visual development of term infants supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA).
DESIGN AND METHODS
The Boyack and Lookinland Methodological Quality Index (MQI) was used to evaluate data from RCTs identified from multiple data bases.
RESULTS
Six of ten studies found the addition of DHA and ARA to have no significant effect on infant development.
PRACTICE IMPLICATIONS
More expensive formula with endogenous DHA and ARA is not necessary. Results from longer studies currently underway will be beneficial.
目的
总结评估补充二十二碳六烯酸（DHA）和花生四烯酸（ARA）的足月儿生长、认知、神经和视觉发育的随机对照试验（RCT）结果。
设计与方法
采用博亚克和卢金兰方法学质量指数（MQI）来评估从多个数据库中识别出的RCT数据。
结果
十项研究中有六项发现添加DHA和ARA对婴儿发育无显著影响。
实践意义
无需使用含有内源性DHA和ARA的更昂贵配方奶粉。目前正在进行的更长时间研究的结果将是有益的。
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