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多目标磁感应断层成像(MIT)逆问题的解决方案:关于重建导电区域的可检测性和统计特性分析

Solution of the inverse problem of magnetic induction tomography (MIT) with multiple objects: analysis of detectability and statistical properties with respect to the reconstructed conducting region.

作者信息

Merwa Robert, Brunner Patricia, Missner Andreas, Hollaus Karl, Scharfetter Hermann

机构信息

Institute for Medical Engineering, Graz University of Technology, Krenngasse 37, 8010 Graz, Austria.

出版信息

Physiol Meas. 2006 May;27(5):S249-59. doi: 10.1088/0967-3334/27/5/S21. Epub 2006 Apr 24.

Abstract

Magnetic induction tomography (MIT) is a technique to image the passive electrical properties (i.e. conductivity, permittivity, permeability) of biological tissues. The inverse eddy current problem is nonlinear and ill-posed, thus a Gauss-Newton one-step method in combination with four different regularization schemes is used to obtain stable solutions. Simulations with 16 excitation coils, 32 receiving coils and different spherical perturbations inside a homogeneous cylinder were computed. In order to compare the statistical properties of the reconstructed results a Monte Carlo study with a SNR of 40 dB and 20 dB was carried out. Simulated conductivity perturbations inside a homogeneous cylinder can be localized and resolved and the results prove the feasibility of difference imaging with MIT.

摘要

磁感应断层成像(MIT)是一种用于对生物组织的无源电学特性(即电导率、介电常数、磁导率)进行成像的技术。逆涡流问题是非线性且不适定的,因此采用高斯 - 牛顿一步法结合四种不同的正则化方案来获得稳定解。对一个均匀圆柱体内部具有16个激励线圈、32个接收线圈以及不同球形扰动的情况进行了模拟计算。为了比较重建结果的统计特性,开展了信噪比分别为40 dB和20 dB的蒙特卡罗研究。均匀圆柱体内模拟的电导率扰动能够被定位和分辨,结果证明了利用MIT进行差分成像的可行性。

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