da Silva Benedito Borges, da Silva Raimundo Gerônimo, Lopes Costa Pedro Vitor, Pires Cleicilene Gomes, da Silva Pinheiro Gevina
Department of Gynecology, Federal University of Piauí, Teresina, Piauí, Brazil.
Gynecol Obstet Invest. 2006;62(2):97-9. doi: 10.1159/000092826. Epub 2006 Apr 20.
Although primary malignant breast lesions are common, tumor metastasis to the breast is rare. Melanoma metastasis to the breast occurs even more rarely.
In the present case report, we describe an adolescent girl with malignant melanoma metastasis to the breast masquerading as fibroadenoma, in which it was impossible to perform differential diagnosis based only on the physical examination and ultrasonographic evaluation. The definitive diagnosis both of the primary and of the metastatic lesion was reached by immunohistochemistry, which revealed positivity to Mart-1 antibody.
Melanoma metastasizing to the breast is occasionally indistinguishable from a benign lesion at ultrasonographic evaluation. Emphasis should be made on the importance of a correct diagnosis prior to therapeutic management.
尽管原发性乳腺恶性病变很常见，但肿瘤转移至乳腺却很罕见。黑色素瘤转移至乳腺的情况更为罕见。
在本病例报告中，我们描述了一名青少年女性，其乳腺发生恶性黑色素瘤转移，临床表现为纤维腺瘤，仅通过体格检查和超声评估无法进行鉴别诊断。通过免疫组织化学对原发性和转移性病变均做出了明确诊断，结果显示对Mart-1抗体呈阳性反应。
在超声评估中，转移至乳腺的黑色素瘤偶尔与良性病变难以区分。在进行治疗管理之前，应强调正确诊断的重要性。
