Heldt Elizeth, Blaya Carolina, Isolan Luciano, Kipper Leticia, Teruchkin Betina, Otto Michael W, Fleck Marcelo, Manfro Gisele G
Program of Anxiety Disorders, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Psychother Psychosom. 2006;75(3):183-6. doi: 10.1159/000091776.
Improvements in quality of life (QoL) as well as symptomatic relief are important outcomes for the treatment of panic disorder (PD). The aim of this study is to assess the impact of brief cognitive behavior group therapy (CBGT) for panic disorder on QoL and to identify the clinical features associated with these changes.
Thirty-six patients with PD refractory to pharmacological treatment took part in a treatment protocol consisting of 12 sessions of CBGT. To evaluate the changes in QoL, the WHOQOL-bref was administered before and after treatment.
Thirty-two patients completed the treatment. Significant improvement in all domains of QoL was observed (p< 0.001), which was associated with reductions in general and anticipatory anxiety (p = 0.018) and agoraphobic avoidance (p = 0.046). Consistent with previous findings, associations between QoL and panic-free status did not reach significance in this small study (p = 0.094).
CBGT was efficacious in the treatment of PD; the symptoms of anticipatory anxiety and avoidance appear to be more important than episodic panic episodes in affecting QoL.
生活质量（QoL）的改善以及症状缓解是惊恐障碍（PD）治疗的重要结果。本研究旨在评估简短认知行为团体疗法（CBGT）对惊恐障碍患者生活质量的影响，并确定与这些变化相关的临床特征。
36名对药物治疗无效的惊恐障碍患者参加了一个由12节CBGT组成的治疗方案。为了评估生活质量的变化，在治疗前后分别进行了世界卫生组织生活质量简表（WHOQOL-bref）测试。
32名患者完成了治疗。观察到生活质量的所有领域均有显著改善（p < 0.001），这与总体焦虑和预期焦虑的减轻（p = 0.018）以及广场恐怖症回避行为的减少（p = 0.046）相关。与先前的研究结果一致，在这项小型研究中，生活质量与无惊恐状态之间的关联未达到显著水平（p = 0.094）。
CBGT对惊恐障碍的治疗有效；预期焦虑和回避症状在影响生活质量方面似乎比发作性惊恐发作更为重要。
