Sartoris A, Cortesina G, Busca G P, Pia F, Giordano C, Bussi M, Amasio E, Pisani P
Istituto Policattedra di Clinica Otorinolaringoiatrica, Università di Torino.
Acta Otorhinolaryngol Ital. 1991;11(3):317-27.
Nasal and paranasal sinus tumors extending through the cribriform plate to the overlying dura of the frontal lobe can be successfully treated by anterior craniofacial resection. During the period from 1986 to 1990, 14 patients (11 males, 3 females, age 18-67) with nasal/paranasal tumors extended to the nasal basis underwent craniofacial resection. From a histological point of view these patients were classified as follows: --8 adenocarcinomas --2 squamous cell carcinomas --2 esthesioneuroblastomas --1 cylindroma --1 haemangiopericytoma. In 6 of the 14 patients post-operative complications were encountered, 3 being resolved. Radical surgery was realised in 12 cases; post-operative radiotherapy was performed in 7. No contraindications were found because of previous chemo- and/or radiotherapy, even if it had been performed as treatment. Four of the patients died because of recurrences between the 6th and 20th month after surgery; 5 patients (all adenocarcinoma subjects) are disease-free respectively 8, 16, 17, 22 and 24 months after surgery.
穿过筛板延伸至额叶上方硬脑膜的鼻腔及鼻窦肿瘤可通过前颅面切除术成功治疗。1986年至1990年期间，14例（男11例，女3例，年龄18 - 67岁）鼻腔/鼻窦肿瘤累及鼻底的患者接受了颅面切除术。从组织学角度来看，这些患者分类如下：——8例腺癌——2例鳞状细胞癌——2例嗅神经母细胞瘤——1例圆柱瘤——1例血管外皮细胞瘤。14例患者中有6例出现术后并发症，其中3例得到解决。12例患者实施了根治性手术；7例患者接受了术后放疗。即便之前进行过化疗和/或放疗作为治疗手段，也未发现因之产生的禁忌证。4例患者在术后第6至20个月因复发死亡；5例患者（均为腺癌患者）分别在术后8、16、17、22和24个月无疾病复发。
