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自体血小板浓缩物及负压封闭引流装置在全膝关节置换术后不愈合中的应用

Autologous platelet concentrate and vacuum-assisted closure device use in a nonhealing total knee replacement.

作者信息

Klayman Myra H, Trowbridge Cody C, Stammers Alfred H, Wolfgang Gary L, Zijerdi David A, Bitterly Thomas J

机构信息

Department of Perfusion Services,Surgery, Geisinger Medical Center, Danville, Pennsylvania 17822, USA.

出版信息

J Extra Corpor Technol. 2006 Mar;38(1):44-7.

Abstract

Following a total knee replacement surgery, a 51-year-old insulin-dependent patient presented with complications of impaired healing and postoperative trauma to the wound site. The inability of this leg wound to heal placed this patient at risk of amputation. Vacuum-assisted closure therapy was initiated at postoperative day 53; after 100 days of protracted wound history a series of treatments with topical platelet concentrates were added to the vacuum assisted closure therapy and conventional wound care therapy. The previous nonhealing wound presented with good granulation and margination that enabled a skin graft with good take on postoperative day 150.

摘要

在全膝关节置换手术后,一名51岁的胰岛素依赖型患者出现了愈合受损和伤口部位术后创伤的并发症。这条腿部伤口无法愈合使该患者面临截肢风险。在术后第53天开始进行负压封闭引流治疗;在经历了100天的漫长伤口治疗过程后,在负压封闭引流治疗和传统伤口护理治疗的基础上增加了一系列局部应用血小板浓缩物的治疗。之前未愈合的伤口出现了良好的肉芽组织和边缘,这使得在术后第150天进行的皮肤移植获得了良好的成功。

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