对心肌梗死患者1年生存期的抑郁情况进行评估。
Depression assessed over 1-year survival in patients with myocardial infarction.
作者信息
Sørensen C, Brandes A, Hendricks O, Thrane J, Friis-Hasché E, Haghfelt T, Bech P
机构信息
The Medical Research Unit, Ringkøbing County, Ringkøbing, Denmark.
出版信息
Acta Psychiatr Scand. 2006 Apr;113(4):290-7. doi: 10.1111/j.1600-0447.2006.00777.x.
OBJECTIVE
To estimate the prevalence of ICD-10 depression using a self-reported questionnaire and to examine if depression is associated with increased 1-year mortality in patients with myocardial infarction (MI).
METHOD
In total, 763 MI-patients completed the Major Depression Inventory at discharge. Information from hospital notes was collected and patients were followed 1 year for re-admission and mortality through national registries.
RESULTS
Seventy-three patients (9.6%) were depressed at discharge. Depression was not a significant independent predictor of mortality; however, there was a significant trend for increasing mortality with increasing severity of the depressive state (P = 0.028). All mortality among depressed patients was in patients with non-Q-wave infarction.
CONCLUSION
Ten per cent of MI-patients fulfilled diagnostic criteria for depression at discharge. There was a significant trend for increasing mortality with increasing severity of the depressive episode. All mortality among depressed patients was seen in patients with non-Q-wave infarction. These findings indicate future studies in selected subgroups of MI-patients.
目的
使用一份自我报告问卷评估国际疾病分类第十版（ICD - 10）中抑郁症的患病率，并检验抑郁症是否与心肌梗死（MI）患者1年死亡率增加相关。
方法
共有763例MI患者在出院时完成了《重度抑郁量表》。收集了医院病历中的信息，并通过国家登记系统对患者进行了1年的随访，以了解再入院情况和死亡率。
结果
73例患者（9.6%）在出院时患有抑郁症。抑郁症并非死亡率的显著独立预测因素；然而，随着抑郁状态严重程度的增加，死亡率有显著上升趋势（P = 0.028）。抑郁症患者的所有死亡均发生在非Q波梗死患者中。
结论
10%的MI患者在出院时符合抑郁症诊断标准。随着抑郁发作严重程度的增加，死亡率有显著上升趋势。抑郁症患者的所有死亡均见于非Q波梗死患者。这些发现表明需要对MI患者的特定亚组进行进一步研究。
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