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婴儿期癫痫综合征

Epilepsy syndromes in infancy.

作者信息

Korff Christian M, Nordli Douglas R

机构信息

Epilepsy Center, Children's Memorial Hospital, Chicago, Illinois 60614-3394, USA.

出版信息

Pediatr Neurol. 2006 Apr;34(4):253-63. doi: 10.1016/j.pediatrneurol.2005.08.005.

DOI:10.1016/j.pediatrneurol.2005.08.005
PMID:16638498
Abstract

An increasing number of infantile epilepsy syndromes have been recognized. However, a significant number of infants (children aged 1-24 months) do not fit in any of the currently used subcategories. This article reviews the clinical presentation, electroencephalographic findings, evolution, and management of the following entities: early infantile epileptic encephalopathy, early myoclonic epilepsy, infantile spasms/West syndrome, severe myoclonic epilepsy of infancy, myoclonic-astatic epilepsy, generalized epilepsy with febrile seizures plus, malignant migrating partial seizures of infancy, hemiconvulsions-hemiplegia-epilepsy, benign myoclonic epilepsy, and benign familial/nonfamilial infantile seizures. Issues related to their classification are addressed.

摘要

越来越多的婴儿癫痫综合征已被认识。然而,相当数量的婴儿(1至24个月大的儿童)并不符合目前使用的任何亚类。本文综述了以下疾病的临床表现、脑电图表现、病情演变及治疗:早期婴儿癫痫性脑病、早期肌阵挛性癫痫、婴儿痉挛症/韦斯特综合征、婴儿严重肌阵挛性癫痫、肌阵挛-失张力性癫痫、伴有热性惊厥附加症的全身性癫痫、婴儿恶性游走性部分性癫痫、偏瘫性惊厥-偏瘫-癫痫、良性肌阵挛性癫痫以及良性家族性/非家族性婴儿惊厥。文中还讨论了与它们分类相关的问题。

相似文献

1
Epilepsy syndromes in infancy.婴儿期癫痫综合征
Pediatr Neurol. 2006 Apr;34(4):253-63. doi: 10.1016/j.pediatrneurol.2005.08.005.
2
Malignant epileptic encephalopathies in children.儿童恶性癫痫性脑病
Baillieres Clin Neurol. 1996 Dec;5(4):765-81.
3
Epileptic syndromes in infancy and childhood.婴幼儿及儿童期癫痫综合征
Curr Opin Neurol. 2008 Apr;21(2):161-6. doi: 10.1097/WCO.0b013e3282f7007e.
4
[Epilepsy beginning in the neonatal period and early infancy].[始于新生儿期和婴儿早期的癫痫]
Rev Neurol. 2004;39(3):251-62.
5
[Epilepsies during the first year of life].[出生后第一年的癫痫]
Rev Neurol. 1997 Oct;25(146):1521-4.
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[Myoclonus and myoclonic epilepsies in childhood].[儿童期肌阵挛和肌阵挛性癫痫]
Rev Neurol. 1999;28(3):278-84.
7
Clinical evaluation and diagnosis of severe epilepsy syndromes of early childhood.儿童早期严重癫痫综合征的临床评估与诊断
J Child Neurol. 2009 Aug;24(8 Suppl):6S-14S. doi: 10.1177/0883073809338151.
8
Idiopathic generalized epilepsies recognized by the International League Against Epilepsy.国际抗癫痫联盟认可的特发性全身性癫痫
Epilepsia. 2005;46 Suppl 9:48-56. doi: 10.1111/j.1528-1167.2005.00313.x.
9
Benign pediatric localization-related epilepsies. Part I. Syndromes in infancy.儿童良性局灶性癫痫。第一部分。婴儿期综合征。
Epileptic Disord. 2006 Sep;8(3):169-83.
10
[Severe myoclonic epilepsy in infancy (Dravet's syndrome). Some genetic aspects].[婴儿严重肌阵挛癫痫(德拉韦综合征)。一些遗传学方面]
Rev Neurol. 2003;37(1):60-3.

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Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome.德雷维特综合征小鼠模型中海马神经发生微环境的改变。
Front Cell Dev Biol. 2020 Jul 21;8:654. doi: 10.3389/fcell.2020.00654. eCollection 2020.
2
Randomized trial of adjunctive topiramate therapy in infants with refractory partial seizures.随机试验辅助托吡酯治疗婴儿耐药性部分性癫痫发作。
Neurology. 2010 Mar 2;74(9):714-20. doi: 10.1212/WNL.0b013e3181d1cd4c. Epub 2010 Jan 20.
3
Dravet syndrome.大田原综合征。
Ital J Pediatr. 2009 Sep 8;35(1):27. doi: 10.1186/1824-7288-35-27.
4
A functional null mutation of SCN1B in a patient with Dravet syndrome.一名患有Dravet综合征的患者中SCN1B的功能性无效突变。
J Neurosci. 2009 Aug 26;29(34):10764-78. doi: 10.1523/JNEUROSCI.2475-09.2009.
5
Developing an animal model for infantile spasms: pathogenesis, problems and progress.建立婴儿痉挛症动物模型:发病机制、问题与进展
Dis Model Mech. 2009 Jul-Aug;2(7-8):329-35. doi: 10.1242/dmm.001883.
6
Infantile seizures: infants are not just little children.婴儿癫痫发作:婴儿并非仅仅是小孩子。
Curr Neurol Neurosci Rep. 2008 Mar;8(2):139-44. doi: 10.1007/s11910-008-0022-1.