Smith D C, Pilliar R M, Metson J B, McIntyre N S
University of Toronto, Faculty of Dentistry, University of Western Ontario, Canada.
J Biomed Mater Res. 1991 Sep;25(9):1069-84. doi: 10.1002/jbm.820250903.
The tissue response to an implant may involve both physical and chemical factors. There is little reliable information on the effects of these parameters and the associated ionic release on the cell-material interaction because the majority of studies have not fully characterized the implant material. In this work surface spectroscopy using ISS, ESCA, and SIMS was carried out on Ti6A14V, Co-Cr-Mo, A12O3, and hydroxyapatite dental implant materials that had been subjected to six commonly used preparative procedures. The results showed that each procedure generated an individualistic composition for the outermost surface of each material. These differences could be significant in cellular and tissue response. Improved understanding of these factors requires defined and reproducible surfaces.
组织对植入物的反应可能涉及物理和化学因素。关于这些参数及其相关离子释放对细胞与材料相互作用的影响，几乎没有可靠的信息，因为大多数研究尚未充分表征植入材料。在这项工作中，对经过六种常用制备程序的Ti6A14V、Co-Cr-Mo、A12O3和羟基磷灰石牙科植入材料进行了使用离子散射谱（ISS）、光电子能谱（ESCA）和二次离子质谱（SIMS）的表面光谱分析。结果表明，每种程序都为每种材料的最外层表面生成了独特的组成。这些差异在细胞和组织反应中可能很显著。要更好地理解这些因素，需要定义明确且可重复的表面。
