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[亚甲蓝在心脏手术后血管麻痹综合征治疗中的应用]

[Methylene blue in the therapy of vasoplegic syndrome after cardiac surgery procedure].

作者信息

Ríha H, Ríhová L, Pind'ák M, Brezina A, Pirk J

机构信息

Klinika anesteziologie a resuscitace - Kardiocentrum IKEM, Praha.

出版信息

Cas Lek Cesk. 2006;145(4):322-4.

Abstract

Vasoplegic syndrome after cardiac surgery with cardiopulmonary bypass is severe complication with high morbidity and mortality. Without appropriate therapy the syndrome advances to the shock state with subsequent multiorgan failure. Basic haemodynamic parameters of vasoplegic syndrome include low systemic vascular resistance with severe hypotension, tachycardia, and normal or increased cardiac output and low filling pressures. In therapy norepinephrine and vasopressin or its analogues are used. Methylene blue is other therapeutic option. The case of successful application of methylene blue for the treatment of vasoplegic syndrome is presented.

摘要

体外循环心脏手术后的血管麻痹综合征是一种严重并发症,发病率和死亡率都很高。若不进行适当治疗,该综合征会发展为休克状态,继而引发多器官功能衰竭。血管麻痹综合征的基本血流动力学参数包括体循环血管阻力降低伴严重低血压、心动过速、心输出量正常或增加以及充盈压降低。治疗时会使用去甲肾上腺素和血管加压素或其类似物。亚甲蓝是另一种治疗选择。本文介绍了成功应用亚甲蓝治疗血管麻痹综合征的病例。

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