Fierz Katharina, Steiger Jürg, Denhaerynck Kris, Dobbels Fabienne, Bock Andreas, De Geest Sabina
Institute of Nursing Science, University of Basel, Basel, Switzerland.
Clin Transplant. 2006 Mar-Apr;20(2):171-8. doi: 10.1111/j.1399-0012.2005.00460.x.
Severe alcohol use is recognized as a major public health concern, even though light to moderate alcohol use might have beneficial effects on health. Alcohol use has been studied to some extent in solid organ transplant populations, yet evidence is lacking on alcohol use and its correlates in the renal transplant population. The aim of this study was therefore to determine the prevalence, severity and correlates of alcohol use in renal transplant recipients.
This cross-sectional study is a secondary analysis of the Supporting Medication Adherence in Renal Transplantation (SMART) study. Alcohol use was assessed by patient's self-report. At risk and binge drinkers were classified using World Health Organization criteria. The following correlates of alcohol use were explored: adherence with immunosuppression (Siegal questionnaire; electronic monitoring), smoking, coping style (UCL), depressive symptomatology (BDI) and busyness/routine in life style (ACQ Busyness Scale).
Two hundred and eighty-four patients were included in this analysis, 58.1% male, with a mean age of 54 yr (range 20-84) and a median of seven (interquartile ranges [IQR] 8) yr post-transplantation. A total of 52.8% of study participants reported to drink alcohol at least once a week. Two hundred and eighty of 284 subjects (98.5%) were drinking at low risk, four at moderate risk (1.5%). None of the participants were drinking severely. Correlates of alcohol use were male gender and being professionally active.
Alcohol use is less prevalent in renal transplant recipients than in the general population. Severe alcohol use does not seem to represent a serious problem in renal transplant patients.
尽管轻度至中度饮酒可能对健康有益,但严重酗酒被视为一个主要的公共卫生问题。在实体器官移植人群中,饮酒情况已得到一定程度的研究,但肾移植人群中饮酒及其相关因素的证据仍很缺乏。因此,本研究的目的是确定肾移植受者中饮酒的患病率、严重程度及其相关因素。
本横断面研究是对肾移植支持性药物依从性(SMART)研究的二次分析。饮酒情况通过患者自我报告进行评估。使用世界卫生组织标准对有风险饮酒者和暴饮者进行分类。探讨了以下饮酒相关因素:免疫抑制依从性(西格尔问卷;电子监测)、吸烟、应对方式(伦敦大学学院问卷)、抑郁症状(贝克抑郁量表)以及生活方式的忙碌程度/日常规律(ACQ忙碌量表)。
本分析纳入了284例患者,其中58.1%为男性,平均年龄54岁(范围20 - 84岁),移植后中位时间为7年(四分位间距[IQR] 8年)。共有52.8%的研究参与者报告至少每周饮酒一次。284名受试者中有280名(98.5%)为低风险饮酒者,4名(1.5%)为中度风险饮酒者。没有参与者为严重酗酒者。饮酒的相关因素为男性性别和职业活跃。
肾移植受者中饮酒的患病率低于一般人群。严重酗酒在肾移植患者中似乎不构成严重问题。