Bragg R R, Allwright D M, Coetzee L
Department of Poultry Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort.
Onderstepoort J Vet Res. 1991 Dec;58(4):309-10.
A drop in egg production associated with loss of pigment and soft-shelled eggs was experienced on a farm in the Western Cape. Investigations revealed high levels of antibodies against adenovirus 127, the causative agent of egg drop syndrome (EDS) in chickens which were not vaccinated against EDS. A cytopathic agent was subsequently isolated in chicken embryo liver cell cultures and identified as EDS virus by haemagglutination inhibition and neutralization tests.
西开普省的一个农场出现了产蛋量下降的情况，同时伴有色素沉着丧失和软壳蛋现象。调查发现，在未接种抗产蛋下降综合征（EDS）疫苗的鸡群中，针对腺病毒127的抗体水平很高，腺病毒127是鸡产蛋下降综合征的病原体。随后，在鸡胚肝细胞培养物中分离出一种细胞病变因子，并通过血凝抑制试验和中和试验鉴定为EDS病毒。
