Chen S H, Chen P Y, Pan S, Lien G S, Yang I F, Huang T S
Department of Internal Medicine, Taipei Medical College, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1991 Dec;48(6):477-80.
Inflammatory mucosal changes of upper gastrointestinal (GI) tract including stomach and duodenum are well documented in uremic patients and assumed to be the major source of upper GI bleeding. However, acute esophageal ulcer which causes massive bleeding on hemodialysis is rare. Herewith a case is reported. A 28-year-old male uremic patient had a sudden onset of hematemesis on hemodialysis. Urgent endoscopy revealed an acute mucosal lesion with bleeding at the upper and middle third esophagus. It was demonstrated by esophageal biopsy. The patient had taken some pepper one day before and was choked during hemodialysis. This special condition is suggested to induce the acute esophageal ulcer and bleeding.
上消化道(GI)包括胃和十二指肠的炎性黏膜变化在尿毒症患者中已有充分记录,并被认为是上消化道出血的主要来源。然而,导致血液透析时大量出血的急性食管溃疡却很罕见。在此报告一例。一名28岁的男性尿毒症患者在血液透析时突然出现呕血。紧急内镜检查发现食管上中三分之一处有急性黏膜病变伴出血。食管活检证实了这一点。该患者在血液透析前一天吃了一些辣椒,并在透析过程中呛到。提示这种特殊情况诱发了急性食管溃疡和出血。