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胸主动脉夹层腔内支架植入术后主动脉直径转归的中期结果:一项多中心研究

Midterm results of aortic diameter outcomes after thoracic stent-graft implantation for aortic dissection: a multicenter study.

作者信息

Gaxotte Virginia, Thony Frédéric, Rousseau Hervé, Lions Christophe, Otal Philippe, Willoteaux Serge, Rodiere Mathieu, Negaiwi Ziad, Joffre Francis, Beregi Jean-Paul

机构信息

Radiologie Vasculaire, Hôpital Cardiologique CHRU Lille, France.

出版信息

J Endovasc Ther. 2006 Apr;13(2):127-38. doi: 10.1583/04-1416R.1.

Abstract

PURPOSE

To evaluate aortic diameter outcomes after stent-graft implantation for aortic dissection in the descending thoracic aorta.

METHODS

Fifty patients with type A dissection after ascending aortic surgery (n = 10), type B dissection (n = 34), or intramural hematoma (n = 6) underwent stent-graft repair in 3 centers. Thrombosis and aortic diameter were analyzed by computed tomographic angiography at different levels of the aorta before stent-graft implantation, at discharge, and at follow-up. Measurements were standardized.

RESULTS

In all, 67 stent-grafts were implanted for acute (n = 18) and chronic (n = 32) dissection. Stent-graft placement was successfully performed with high technical success (100%) despite 4 major complications (iliac thrombosis in 2 cases, aortic rupture, and a type A dissection) in 3 (6%) patients. Complete thrombosis of the thoracic false lumen was observed in 42% and 63% of cases at discharge and at follow-up (mean 15 months), respectively. At follow-up, the diameters of the entire aorta (mean 5 mm, p < 0.05) and the false lumen (mean 11 mm, p < 0.0001) decreased. Diameters of the abdominal aorta remained stable in association with persistent false lumen perfusion at this level. Aortic diameter results were better in the subgroup of patients with intramural hematoma compared to patients with Marfan syndrome. Three early deaths unrelated to the stent-graft procedure occurred; 2 patients with partial thrombosis of the false lumen died in follow-up secondary to aortic diameter growth.

CONCLUSION

Complete thrombosis of the false lumen by stent-graft coverage of the entry tear results in decreased diameter of the entire aorta. In patients with partial thrombosis of the false lumen, the aneurysm continues to enlarge.

摘要

目的

评估降主动脉夹层支架植入术后的主动脉直径变化情况。

方法

50例升主动脉手术后A型夹层(n = 10)、B型夹层(n = 34)或壁内血肿(n = 6)患者在3个中心接受了支架植入修复术。在支架植入前、出院时及随访时,通过计算机断层血管造影分析主动脉不同水平的血栓形成情况及主动脉直径。测量方法标准化。

结果

共植入67枚支架用于急性(n = 18)和慢性(n = 32)夹层。尽管3例(6%)患者出现4例主要并发症(2例髂静脉血栓形成、主动脉破裂和1例A型夹层),但支架植入技术成功率仍高达100%。出院时和随访时(平均15个月)分别有42%和63%的病例观察到胸段假腔完全血栓形成。随访时,整个主动脉直径(平均减少5 mm,p < 0.05)和假腔直径(平均减少11 mm,p < 0.0001)均减小。腹主动脉直径保持稳定,该水平假腔持续灌注。与马方综合征患者相比,壁内血肿患者亚组的主动脉直径结果更好。发生了3例与支架植入手术无关的早期死亡;2例假腔部分血栓形成的患者在随访中因主动脉直径增大死亡。

结论

通过支架覆盖入口撕裂实现假腔完全血栓形成可使整个主动脉直径减小。在假腔部分血栓形成的患者中,动脉瘤仍会继续扩大。

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