Gao Yong-Shan, Zhang Zhen-Ming, Jin Feng-Xian, Dong Yue-Hua, Jiang Wei-Hua, Wang Da-Wei, Wei Yu-Lei
Department of Thoracic and Cardiovascular Surgery, the First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2021 Jan;52(1):111-116. doi: 10.12182/20210160207.
To investigate the characteristics of aortic remodeling after thoracic endovascular aortic repair using two-stent graft implantation (TEVAR-TSI) for Stanford B aortic dissection.
The clinical and imaging data of 128 patients who underwent TEVAR-TSI for Stanford B aortic dissection in the First Affiliated Hospital of Hebei North University from January 2013 through May 2019 were retrospectively collected. CT images were obtained before (T ) TEVAR-TSI and, 1 week (T ), 3 months (T ), 6 months (T ), 1 year (T ) after TEVAR-TSI. The maximum diameter of the true lumen and false lumen in the short axis view was accessed at five levels: L : the level of primary tear entry, L : the level of the bronchial bifurcation, L : the level of the distal of the first stent-graft, L : the level of the celiac trunk, L : the level of the lowest renal arteries. The false lumen thrombosis in the thoracic aorta and abdominal aorta were assessed at different times, the false lumen and true lumen changes in diameter were evaluated between the preoperative and postoperative CT scan.
The stented segment of the descending thoracic aorta was evaluated (L -L ): The true lumen diameter showed an increasing trend and the false lumen diameter showed an decreasing trend at levels L , L , and L , the change of true lumen diameter was positively correlated with the follow-up time ( =0.721, 0.827, 0.893, <0.05), and the change rate of true lumen diameter was positively correlated with the follow-up time ( =0.763, 0.818, 0.902, <0.05), and the change of false lumen diameter was negatively correlated with the follow-up time ( =-0.750, -0.927, -0.934, <0.05), and the change rate of false lumen diameter was negatively correlated with the follow-up time (-0.774, -0.935, -0.952, <0.05). When the unstented segment of the abdominal aorta was evaluated (L -L ), the average true lumen diameter at the level of celiac trunk increased significantly at 1 year by 13.7% ( =0.007), however, the average false lumen diameter did not change over time ( =0.406). The average true lumen diameter and false lumen diameter at the level of the lowest renal arteries increased over time as well, the average true lumen increased by 10.1%, and the average false lumen increased by 13.6% ( =0.048, 0.017). Besides, the complete false lumen thrombosis rate of the stented segment of the descending thoracic aorta was higher than that of the unstented segment of the abdominal aorta.e complete false lumen thrombosis rate of the stented segment of the descending thoracic aorta was higher than that of the unstented segment of the abdominal aorta.
After receiving TEVAR-TSI, Stanford type B aortic dissection patients had high thrombosis absorption rate in the thoracic aortic segment covered by stent, and the aortic remodeling was more ideal. The aortic remodeling effect in the abdominal aortic segment not covered was not ideal, and the inner diameter of the abdominal aorta tended to increase. Therefore, close follow-up monitoring should be conducted.
探讨采用双支架植入术(TEVAR-TSI)治疗Stanford B型主动脉夹层后主动脉重塑的特点。
回顾性收集2013年1月至2019年5月在河北北方学院附属第一医院接受TEVAR-TSI治疗的128例Stanford B型主动脉夹层患者的临床和影像学资料。在TEVAR-TSI术前(T)以及术后1周(T)、3个月(T)、6个月(T)、1年(T)获取CT图像。在五个层面测量短轴视图下真腔和假腔的最大直径:L:原发破口入口层面,L:支气管分叉层面,L:第一个支架移植物远端层面,L:腹腔干层面,L:最低肾动脉层面。评估不同时间胸主动脉和腹主动脉的假腔血栓形成情况,比较术前和术后CT扫描时假腔和真腔直径的变化。
对胸降主动脉带支架节段(L-L)进行评估:在L、L和L层面,真腔直径呈增加趋势,假腔直径呈减小趋势,真腔直径变化与随访时间呈正相关(=0.721、0.827、0.893,<0.05),真腔直径变化率与随访时间呈正相关(=0.763、0.818、0.902,<0.05),假腔直径变化与随访时间呈负相关(=-0.750、-0.927、-0.934,<0.05),假腔直径变化率与随访时间呈负相关(-0.774、-0.935、-0.952,<0.05)。对腹主动脉无支架节段(L-L)进行评估时,腹腔干层面1年时真腔平均直径显著增加13.7%(=0.007),然而,假腔平均直径随时间无变化(=0.406)。最低肾动脉层面真腔和假腔平均直径也随时间增加,真腔平均增加10.1%,假腔平均增加13.6%(=0.048、0.017)。此外,胸降主动脉带支架节段的假腔完全血栓形成率高于腹主动脉无支架节段。胸降主动脉带支架节段的假腔完全血栓形成率高于腹主动脉无支架节段。
接受TEVAR-TSI治疗后,Stanford B型主动脉夹层患者支架覆盖的胸主动脉段血栓吸收率高,主动脉重塑更理想。未覆盖的腹主动脉段主动脉重塑效果不理想,腹主动脉内径有增大趋势。因此,应进行密切的随访监测。