Díez-Domingo Javier, Martín Itziar Oyagüez, Sanz Alfredo Ballester, López Antonio Gónzalez, Martínez Carmen Casaní, Boronat Carmen Peidró, Del Barrio M Jesús Muñoz, García Dolores Gallego, Pons Manuel Martínez, Crespo Vicente Antón, Esteve Pilar Albors, Arfella Inmaculada Latorre, Monrabal Ignacio Sorribes, Baveira Luis Blesa, López Mercedes García
Vaccine Area, Center for Public Health Research, Vaccine Institute of Valencia, Spain.
Pediatr Infect Dis J. 2006 May;25(5):455-7. doi: 10.1097/01.inf.0000217378.30444.21.
The population-based incidence of rotavirus gastroenteritis in children <5 years of age in Valencia, Spain, over a 1-year period (December 1, 2003, to November 30, 2004) was determined.A total of 553 episodes of gastroenteritis in children <5 years of age (mean age, 22.8 +/- 14.5 months) were recorded (annual incidence of 138 per 1,000). A positive enzyme-linked immunoadsorbant assay result for rotavirus antigen was obtained in 15% of the samples. The incidence of rotavirus gastroenteritis was 15 per 1,000 children <5 years of age, being the highest incidence in children <or=12 months of age (31 per 1,000). Eighty percent of rotavirus gastroenteritis occurred during the winter months (January-March). Genotype G1 was detected in 86% of the samples and G4 in the other 14%.
确定了西班牙巴伦西亚1年内（2003年12月1日至2004年11月30日）5岁以下儿童轮状病毒肠胃炎的人群发病率。共记录了553例5岁以下儿童肠胃炎发作（平均年龄22.8±14.5个月）（年发病率为每1000人138例）。15%的样本中轮状病毒抗原的酶联免疫吸附测定结果呈阳性。5岁以下儿童轮状病毒肠胃炎的发病率为每1000人15例，其中12个月及以下儿童发病率最高（每1000人31例）。80%的轮状病毒肠胃炎发生在冬季月份（1月至3月）。86%的样本中检测到G1基因型，其他14%检测到G4基因型。
