Dvirskiĭ A E, Shevtsov A G
Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(6):28-30.
A study was made of the effect of hereditary loading with schizophrenia on the clinical characteristics of epilepsy. In the population sample of epileptic patients (n = 3489), hereditary loading with schizophrenia was revealed in 4.7% of the patients, among whom loading with both schizophrenia and epilepsy was recorded in 0.6% of the cases. The clinical manifestations of epilepsy were compared in 143 patients loaded with schizophrenia and in 158 patients without hereditary loading with mental diseases. It has been established that in epileptic patients, the factor of hereditary loading with schizophrenia exerts a modifying effect on the premorbid characteristics, increasing the rate of schizoepileptoid, schizoid, and astheno-neurotic++ personality traits, and contributes to a favorable course of the disease. The data obtained standpoint of the previously advanced ++clinico-genetic concept of combined psychoses.
一项关于精神分裂症遗传负荷对癫痫临床特征影响的研究。在癫痫患者的总体样本（n = 3489）中，4.7%的患者存在精神分裂症遗传负荷，其中0.6%的病例同时存在精神分裂症和癫痫遗传负荷。对143例有精神分裂症遗传负荷的癫痫患者和158例无精神疾病遗传负荷的癫痫患者的癫痫临床表现进行了比较。结果表明，在癫痫患者中，精神分裂症遗传负荷因素对病前特征具有修饰作用，增加了精神分裂癫痫样、类精神分裂症和衰弱神经症++人格特质的发生率，并有助于疾病的良好转归。这些数据是从先前提出的++联合精神病临床遗传概念的角度获得的。
