Nilstun Tore, Hermerén Göran
Department of Medical Ethics, Lund University, SE-222 22, Lund, Sweden.
Med Health Care Philos. 2006;9(1):81-6. doi: 10.1007/s11019-005-7984-4.
To survey the attitudes of the general public in Sweden to biobank research and to discuss the findings in the light of some well-known ethical principles.
A questionnaire was used to survey the opinions of the general public in Sweden, and an ethical analysis (using the principles of autonomy, non-maleficence, beneficence and justice) was performed to discuss the possible conditions of such research.
Between 3 and 9% answered that they did not want their samples to be collected and stored in a biobank. Many respondents required information about the purpose of the research and wanted to be able to consent or refuse. About one third of the respondents said they would have answered differently if financial gain was involved and those who commented indicated a more negative attitude. The principle of autonomy maintains that the right to self-determination should be respected, and the principles of non-maleficence and beneficence that the probable harms and benefits resulting from a particular project by using samples from a biobank should be balanced. The general public disagree about how these principles are to be balanced.
In the light of the findings different interpretations of the situation as well as possible alternatives are discussed in this paper.
调查瑞典公众对生物样本库研究的态度，并根据一些著名的伦理原则对调查结果进行讨论。
采用问卷调查瑞典公众的意见，并进行伦理分析（运用自主、不伤害、有益和公正原则）以讨论此类研究的可能条件。
3%至9%的受访者表示不希望自己的样本被采集并存储在生物样本库中。许多受访者要求了解研究目的，并希望能够同意或拒绝。约三分之一的受访者表示，如果涉及经济利益，他们的回答会有所不同，且发表评论者态度更为负面。自主原则主张应尊重自决权，不伤害和有益原则主张使用生物样本库样本的特定项目所产生的可能危害和益处应保持平衡。公众对于如何平衡这些原则存在分歧。
根据研究结果，本文讨论了对该情况的不同解读以及可能的替代方案。
