Klimova T T, Sanadze A G, Skoromets A A, Khliustova O V
Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(9):25-7.
Seventeen patients with generalized myasthenia were treated by the enterosorbent vaulen for 20 days. Of these, 12 patients manifested an appreciable improvement of the well-being shown up by the enhancement of the power of oculomotor, mimic, bulbar, respiratory and body musculature. As a result of the treatment, the dose of anticholinesterase drugs was reduced 2-fold in 12 patients. The intake of these drugs could be fully discontinued in 3 patients. The clinically detectable improvement correlated with an increase of the amplitude of M-response and a reduction of the amplitude decrement during stimulation at a frequency of 3 imp/s. No changes in the electrolyte composition of the blood and protein fractions or other side effects of the drug were discovered. The data obtained served the basis for recommending enterosorption as one of the methods in a complex of treatment measures for patients suffering from myasthenia.
17例全身性重症肌无力患者接受肠吸附剂沃伦治疗20天。其中，12例患者的健康状况有明显改善，表现为动眼、表情、延髓、呼吸及身体肌肉力量增强。治疗后，12例患者的抗胆碱酯酶药物剂量减少了一半。3例患者可完全停用这些药物。临床可检测到的改善与M反应幅度增加及在3次/秒刺激频率下刺激期间幅度递减减少相关。未发现血液电解质成分、蛋白质组分或药物的其他副作用有变化。所获数据为推荐肠吸附作为重症肌无力患者综合治疗措施之一提供了依据。
