两种猫白血病病毒分离株对猫骨髓成纤维细胞集落形成单位的可变抑制作用
Variable suppression of feline bone marrow fibroblast colony-forming units by two isolates of feline leukemia virus.
作者信息
Wellman M L, Kociba G J, Mathes L E
机构信息
Department of Veterinary Pathobiology, College of Veterinary Medicine, Ohio State University, Columbus 43210.
出版信息
Am J Vet Res. 1991 Nov;52(11):1924-7.
Bone marrow fibroblast colony-forming units (CFU-F) were evaluated in cats experimentally infected with different, isolates of FeLV. Cats infected with the Kawakami-Theilen isolate of FeLV (FeLV-KT) had progressive decrease in the number of CFU-F at 2, 4, and 6 weeks after infection. The number of CFU-F in FeLV-KT-infected cats ranged from 38 to 70% of the preinoculation CFU-F value. Of 3 cats with FeLV-KT-induced suppression of CFU-F, 2 developed fatal nonregenerative anemia. Cats infected with the Rickard isolate of FeLV (FeLV-R) had more moderate decrease in the number of CFU-F at 2, 4, and 6 weeks after infection. The number of CFU-F in FeLV-R-infected cats ranged from 62 to 82% of the preinoculation CFU-F value. The FeLV-R-infected cats did not become anemic.
对实验感染不同猫白血病病毒（FeLV）分离株的猫进行了骨髓成纤维细胞集落形成单位（CFU-F）评估。感染川上-泰伦FeLV分离株（FeLV-KT）的猫在感染后2周、4周和6周时CFU-F数量逐渐减少。FeLV-KT感染猫的CFU-F数量为接种前CFU-F值的38%至70%。在3只因FeLV-KT导致CFU-F受抑制的猫中，2只发展为致命的非再生性贫血。感染里卡德FeLV分离株（FeLV-R）的猫在感染后2周、4周和6周时CFU-F数量有更中度的减少。FeLV-R感染猫的CFU-F数量为接种前CFU-F值的62%至82%。FeLV-R感染的猫没有出现贫血。
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