Chang Eugene Y, Johnson William, Karamlou Kasra, Khaki Ali, Komanapalli Christopher, Walts Deb, Mahin Diana, Johnson Nathalie
Legacy Cancer Services, Surgical Associates, 1130 N.W. 22nd St., Ste. 500, Portland, OR 97210, USA.
Am J Surg. 2006 May;191(5):641-5. doi: 10.1016/j.amjsurg.2006.01.036.
Breast cancer patients with pulmonary lesions are often assumed to have metastatic disease and treated palliatively. We evaluated the proportion of these patients who actually have primary lung tumor (PLT) and assessed their outcome.
We performed a 10-year retrospective review of the cancer registry in a community hospital system.
Among 54 breast cancer patients with pulmonary nodules, biopsy was pursued in 30. Although metastatic breast cancer (MBC) was presumed in 24, biopsy showed MBC in 9 patients and PLT in 21. The two groups differed in age, stage, breast tumor size, nodal involvement, and estrogen receptor (ER) positivity. However, no variable excluded the possibility of PLT. Of those with PLT, 11 had early-stage lung disease; 9 underwent curative resection.
Women with breast cancer and 1 or more pulmonary lesions without evidence of other metastatic disease require work-up of pulmonary lesions. Aggressive evaluation can afford treatment of lung cancer and impact survival.
患有肺部病变的乳腺癌患者通常被认为患有转移性疾病并接受姑息治疗。我们评估了这些患者中实际患有原发性肺肿瘤（PLT）的比例，并评估了他们的预后。
我们对一家社区医院系统的癌症登记处进行了为期10年的回顾性研究。
在54例患有肺结节的乳腺癌患者中，30例进行了活检。虽然24例被推测为转移性乳腺癌（MBC），但活检显示9例为MBC，21例为PLT。两组在年龄、分期、乳腺肿瘤大小、淋巴结受累情况和雌激素受体（ER）阳性方面存在差异。然而，没有任何变量可以排除PLT的可能性。在患有PLT的患者中，11例患有早期肺部疾病；9例接受了根治性切除术。
患有乳腺癌且有1个或更多肺部病变且无其他转移性疾病证据的女性需要对肺部病变进行检查。积极的评估可以为肺癌的治疗提供机会并影响生存。
