• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

成人自发性脑脊液耳漏:与影像学空蝶鞍的相关性。

Adult spontaneous CSF otorrhea: correlation with radiographic empty sella.

作者信息

Prichard Christopher N, Isaacson Brandon, Oghalai John S, Coker Newton J, Vrabec Jeffrey T

机构信息

Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas 77030, USA.

出版信息

Otolaryngol Head Neck Surg. 2006 May;134(5):767-71. doi: 10.1016/j.otohns.2006.01.002.

DOI:10.1016/j.otohns.2006.01.002
PMID:16647532
Abstract

OBJECTIVE

To determine the prevalence of radiographic empty sella in patients with spontaneous cerebrospinal fluid (CSF) otorrhea.

STUDY DESIGN AND SETTING

Retrospective case series of adult patients with CSF otorhinorrhea at an academic tertiary medical center. Patients with history of skull base surgery, trauma, tumor, or chronic ear disease were excluded. Available imaging studies were reviewed with attention to the sella turcica.

RESULTS

Eight patients were diagnosed with spontaneous CSF otorrhea. Five of seven patients with adequate imaging studies (71%) had a radiographic empty sella. Seven of eight patients were clinically obese, with a body mass index BMI>30 kg/m2.

CONCLUSIONS

Empty sella is a common radiologic finding in patients with spontaneous CSF otorrhea. This supports the theory that increased intracranial pressure contributes to development of spontaneous CSF otorrhea.

SIGNIFICANCE

Radiographic empty sella predicts elevated intracranial pressure, which may require further evaluation and treatment in patients with spontaneous CSF otorrhea.

EBM RATING

C-4.

摘要

目的

确定自发性脑脊液耳漏患者中影像学空蝶鞍的患病率。

研究设计与背景

在一家学术性三级医疗中心对成年脑脊液耳鼻漏患者进行回顾性病例系列研究。排除有颅底手术、创伤、肿瘤或慢性耳部疾病史的患者。对现有的影像学研究进行回顾,重点关注蝶鞍。

结果

8例患者被诊断为自发性脑脊液耳漏。7例有充分影像学研究的患者中有5例(71%)存在影像学空蝶鞍。8例患者中有7例临床肥胖,体重指数(BMI)>30 kg/m²。

结论

空蝶鞍是自发性脑脊液耳漏患者常见的影像学表现。这支持了颅内压升高导致自发性脑脊液耳漏发生的理论。

意义

影像学空蝶鞍预示颅内压升高,这可能需要对自发性脑脊液耳漏患者进行进一步评估和治疗。

循证医学评级

C-4。

相似文献

1
Adult spontaneous CSF otorrhea: correlation with radiographic empty sella.成人自发性脑脊液耳漏:与影像学空蝶鞍的相关性。
Otolaryngol Head Neck Surg. 2006 May;134(5):767-71. doi: 10.1016/j.otohns.2006.01.002.
2
New considerations in the cause of spontaneous cerebrospinal fluid otorrhea.自发性脑脊液耳漏病因的新考虑因素。
Otol Neurotol. 2010 Aug;31(6):940-5. doi: 10.1097/mao.0b013e3181e8f36c.
3
Spontaneous nasal cerebrospinal fluid leaks and empty sella syndrome: a clinical association.自发性鼻脑脊液漏与空蝶鞍综合征:一种临床关联。
Am J Rhinol. 2003 Mar-Apr;17(2):91-6.
4
ICP, BMI, surgical repair, and CSF diversion in patients presenting with spontaneous CSF otorrhea.伴有自发性脑脊液耳漏患者的 ICP、BMI、手术修复和 CSF 引流。
Otol Neurotol. 2014 Feb;35(2):344-7. doi: 10.1097/MAO.0b013e3182a473cf.
5
Significance of empty sella in cerebrospinal fluid leaks.空蝶鞍在脑脊液漏中的意义。
Otolaryngol Head Neck Surg. 2003 Jan;128(1):32-8. doi: 10.1067/mhn.2003.43.
6
Management of spontaneous cerebrospinal fluid otorrhea.自发性脑脊液耳漏的管理
Laryngoscope. 2008 Dec;118(12):2195-9. doi: 10.1097/MLG.0b013e318182f833.
7
Elevated intracranial pressures in spontaneous cerebrospinal fluid leaks.自发性脑脊液漏中的颅内压升高
Am J Rhinol. 2003 Jul-Aug;17(4):191-5.
8
Spontaneous cerebrospinal fluid otorrhea and rhinorrhea in idiopathic intracranial hypertension patients.特发性颅内高压患者的自发性脑脊液耳漏和鼻漏。
J Neuroophthalmol. 2013 Jun;33(2):113-6. doi: 10.1097/WNO.0b013e18274b870.
9
Association between Lateral Skull Base Thickness and Surgical Outcomes in Spontaneous CSF Otorrhea.自发性脑脊液耳漏患者颅底外侧厚度与手术结果的相关性
Otolaryngol Head Neck Surg. 2016 Apr;154(4):707-14. doi: 10.1177/0194599816628528. Epub 2016 Feb 23.
10
Are Patients with Spontaneous CSF Otorrhea and Superior Canal Dehiscence Congenitally Predisposed to Their Disorders?自发性脑脊液耳漏伴内听道顶壁骨缺损患者是否存在先天易患倾向?
Otolaryngol Head Neck Surg. 2018 Sep;159(3):543-552. doi: 10.1177/0194599818769875. Epub 2018 Apr 24.

引用本文的文献

1
A Rare Case of Non-traumatic Tension Pneumocephalus Following a Lumbar Puncture: Unusual Complications of a Common Procedure.腰椎穿刺后非创伤性张力性气颅一例:常见操作的罕见并发症
Cureus. 2025 Apr 24;17(4):e82888. doi: 10.7759/cureus.82888. eCollection 2025 Apr.
2
Idiopathic Intracranial Hypertension Is Associated with Recurrent CSF Leak and Reoperation for Spontaneous Temporal Encephalocele.特发性颅内高压与复发性脑脊液漏及自发性颞叶脑膨出再手术有关。
J Neurol Surg B Skull Base. 2023 Nov 28;85(Suppl 2):e50-e56. doi: 10.1055/a-2198-8374. eCollection 2024 Oct.
3
A Comparison of Diagnostic Accuracy of Superior Semicircular Canal Dehiscence in MDCT and MRI, and Coexistence with Tegmen Tympani Dehiscence.
MDCT与MRI诊断上半规管裂的准确性比较及与鼓室盖裂并存情况
J Neurol Surg B Skull Base. 2020 Jul 15;82(4):476-483. doi: 10.1055/s-0040-1714107. eCollection 2021 Aug.
4
Deossification of the Otic Bone in High Pressure CSF Otorhinorrhea: A New Radiological Finding.高压性脑脊液耳鼻漏中耳骨脱钙:一项新的影像学发现。
Indian J Otolaryngol Head Neck Surg. 2020 Sep;72(3):385-391. doi: 10.1007/s12070-019-01777-w. Epub 2020 Jan 2.
5
In Patients with Unexplained Non-Epidemic Recurrent Meningitis a Direct Communication between the Subarachnoid Space and the Outside Must Be Sough.对于不明原因的非流行性复发性脑膜炎患者,必须探寻蛛网膜下腔与外界之间的直接连通情况。
J Int Adv Otol. 2019 Aug;15(2):313-316. doi: 10.5152/iao.2019.4208.
6
Do Most Patients With a Spontaneous Cerebrospinal Fluid Leak Have Idiopathic Intracranial Hypertension?大多数自发性脑脊液漏患者都患有特发性颅内高压吗?
J Neuroophthalmol. 2019 Dec;39(4):487-495. doi: 10.1097/WNO.0000000000000761.
7
Surgical Outcomes and Postoperative Management in Spontaneous Cerebrospinal Fluid Rhinorrhea.自发性脑脊液鼻漏的手术疗效及术后管理
J Neurol Surg B Skull Base. 2018 Apr;79(2):193-199. doi: 10.1055/s-0037-1606306. Epub 2017 Sep 4.
8
Petrous apex cephalocoele: contribution of coexisting intracranial pathologies to the aetiopathogenesis.岩尖脑膨出:并存的颅内病变对病因发病机制的作用
Br J Radiol. 2015 Apr;88(1048):20140721. doi: 10.1259/bjr.20140721. Epub 2015 Feb 4.
9
Combined approach for tegmen defects repair in patients with cerebrospinal fluid otorrhea or herniations: our experience.脑脊液耳漏或脑膨出患者中 tegmen 缺损修复的联合方法:我们的经验
J Neurol Surg B Skull Base. 2014 Aug;75(4):279-87. doi: 10.1055/s-0034-1371524. Epub 2014 May 2.
10
Spontaneous lateral sphenoid cephaloceles: anatomic factors contributing to pathogenesis and proposed classification.自发性蝶骨外侧颅底脑膨出:发病机制的解剖学因素及分类建议。
AJNR Am J Neuroradiol. 2014 Apr;35(4):784-9. doi: 10.3174/ajnr.A3744. Epub 2013 Oct 3.