正常孕期脉搏波速度的变化及其在预测妊娠期高血压中的价值：一项纵向研究。
Change in pulse wave velocity throughout normal pregnancy and its value in predicting pregnancy-induced hypertension: a longitudinal study.
作者信息
Oyama-Kato Mizuho, Ohmichi Masahide, Takahashi Kazuhiro, Suzuki Sachiko, Henmi Noriko, Yokoyama Yukio, Kurachi Hirohisa
机构信息
Department of Obstetrics and Gynecology, Yamagata University School of Medicine, Iidanishi, Yamagata, Japan.
出版信息
Am J Obstet Gynecol. 2006 Aug;195(2):464-9. doi: 10.1016/j.ajog.2006.01.104. Epub 2006 May 2.
OBJECTIVE
We longitudinally examined the changes of brachial to ankle distensibility using pulse wave velocity (PWV) throughout pregnancy and its difference between normal pregnancy and pregnancy-induced hypertension (PIH) groups.
STUDY DESIGN
One hundred and eighty-three pregnant women were included in this study. The PWV examinations were performed in a longitudinal way during the first, second, and third trimesters of pregnancy, and immediately and 1 month after delivery.
RESULTS
In normal pregnancies, the PWV significantly decreased at the second trimester, increased from the third trimester through immediately after delivery, and decreased again at 1 month after delivery. In PIH patients, it increased in proportion to the progression of gestation.
CONCLUSION
We monitored the longitudinal changes in PWV and constructed a PWV normogram during pregnancy. The predictive value of PWV and blood pressure for PIH was higher than that of blood pressure alone, suggesting the usefulness of measuring PWV to predict PIH.
目的
我们纵向研究了整个孕期使用脉搏波速度（PWV）测量的肱踝扩张性变化，以及正常妊娠组和妊娠期高血压（PIH）组之间的差异。
研究设计
本研究纳入了183名孕妇。在妊娠的第一、第二和第三个 trimester 期间，以及分娩后立即和分娩后1个月进行纵向PWV检查。
结果
在正常妊娠中，PWV在妊娠中期显著降低，从妊娠晚期到分娩后立即升高，并在分娩后1个月再次降低。在PIH患者中，它随着妊娠进展而升高。
结论
我们监测了PWV的纵向变化，并构建了孕期PWV正常值图。PWV和血压对PIH的预测价值高于单独血压，表明测量PWV对预测PIH有用。
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