Gross Gil J, Chiu Christine C, Hamilton Robert M, Kirsh Joel A, Stephenson Elizabeth A
Cardiology Division, Hospital for Sick Children, Toronto, Ontario, Canada.
Heart Rhythm. 2006 May;3(5):601-4. doi: 10.1016/j.hrthm.2006.01.023. Epub 2006 Feb 28.
After half a century of major progress in congenital heart disease management, atrioventricular conduction block continues to complicate 1-3% of surgical procedures. Unless treated with an implanted pacemaker, permanent postoperative heart block is associated with 28-100% mortality. Postoperative heart block often proves to be transient, typically resolving within 10 days of onset. The duration of postoperative heart block is widely used as a key determinant for permanent pacemaker implantation. Current professional pacemaker implantation guidelines are largely based on this criterion. However, available natural history data suggest that other factors, such as residual conduction system injury, likely play a role in increasingly recognized cases of very late postoperative mortality and morbidity in patients who have experienced transient postoperative heart block. As growing numbers of congenital heart disease patients survive into adulthood, and artificial pacemaking capabilities continue to improve, it might be necessary to reconsider and refine currently accepted pacing indications for postoperative heart block.
在先天性心脏病治疗取得半个世纪的重大进展之后,房室传导阻滞仍使1%至3%的外科手术复杂化。除非植入起搏器进行治疗,永久性术后心脏传导阻滞的死亡率为28%至100%。术后心脏传导阻滞往往是短暂的,通常在发病后10天内缓解。术后心脏传导阻滞的持续时间被广泛用作永久性起搏器植入的关键决定因素。当前的专业起搏器植入指南很大程度上基于这一标准。然而,现有的自然史数据表明,其他因素,如残留的传导系统损伤,可能在越来越多的术后短暂性心脏传导阻滞患者出现的极晚期术后死亡率和发病率病例中起作用。随着越来越多的先天性心脏病患者存活至成年,且人工起搏能力不断提高,可能有必要重新考虑并完善目前公认的术后心脏传导阻滞起搏指征。