移植：多瘤病毒肾病与特定免疫抑制方案的风险
Transplantation: polyomavirus nephropathy and the risk of specific immunosuppression regimens.
作者信息
Wu Christine, Randhawa Parmjeet, McCauley Jerry
机构信息
Department of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, PA, USA.
出版信息
ScientificWorldJournal. 2006 Apr 28;6:512-28. doi: 10.1100/tsw.2006.93.
BK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community. First discovered in 1971 in the urine of a renal transplant recipient, BK virus nephropathy (BKVN) has come to be recognized as a significant cause of genitourinary disease and potential graft loss in the kidney transplant patient. In this review, we discuss the risk factors, available methods of diagnosis and therapeutic monitoring, and current approaches to therapy of BKVN.
BK病毒以潜伏状态普遍存在于人类体内，肾移植领域对BK多瘤病毒重要性的认识正在不断提高。BK病毒肾病（BKVN）于1971年首次在一名肾移植受者的尿液中被发现，现已被公认为是导致肾移植患者泌尿生殖系统疾病和移植肾潜在丢失的重要原因。在这篇综述中，我们讨论了BKVN的危险因素、现有的诊断和治疗监测方法以及当前的治疗方法。
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