Suppr超能文献

[心脏骤停后用于神经保护的轻度低温治疗]

[Mild hypothermia for neuroprotection after cardiac arrest].

作者信息

Kluge Stefan, Kreymann Georg

机构信息

Medizinische Intensivstation, Klinik für Intensivmedizin, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg.

出版信息

Med Klin (Munich). 2006 Mar 15;101(3):203-7. doi: 10.1007/s00063-006-1025-9.

Abstract

The favorable effect of hypothermia on brain damage resulting from cardiac arrest was first demonstrated in animal studies. Subsequent small-scale human studies have also shown positive effects. In 2002, two large randomized studies investigating the use of controlled mild hypothermia after resuscitation were published in the New England Journal of Medicine. The results convincingly showed a positive effect on survival and neurologic outcome. Based on the currently available data, the International Liaison Committee on Resuscitation (ILCOR) strongly recommends that unconscious adult patients who are resuscitated after ventricular fibrillation be cooled to temperatures between 32 and 34 degrees C for 12-24 h.

摘要

低温对心脏骤停所致脑损伤的有益作用首先在动物研究中得到证实。随后的小规模人体研究也显示出积极效果。2002年,两项关于复苏后使用控制性轻度低温的大型随机研究发表在《新英格兰医学杂志》上。结果令人信服地表明其对生存和神经功能结局有积极影响。基于目前可得的数据,国际复苏联合委员会(ILCOR)强烈建议,心室颤动复苏后的成年昏迷患者应将体温降至32至34摄氏度,并维持12 - 24小时。

相似文献

1
[Mild hypothermia for neuroprotection after cardiac arrest].
Med Klin (Munich). 2006 Mar 15;101(3):203-7. doi: 10.1007/s00063-006-1025-9.
2
Therapeutic hypothermia after cardiac arrest.
Curr Opin Crit Care. 2006 Jun;12(3):213-7. doi: 10.1097/01.ccx.0000224864.93829.d4.
3
Hypothermia after cardiac arrest: expanding the therapeutic scope.
Crit Care Med. 2009 Jul;37(7 Suppl):S227-33. doi: 10.1097/CCM.0b013e3181aa5d0c.
5
Critical time window for intra-arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation.
Circulation. 2006 Jun 13;113(23):2690-6. doi: 10.1161/CIRCULATIONAHA.106.613349.
6
Therapeutic hypothermia after cardiac arrest in clinical practice: review and compilation of recent experiences.
Crit Care Med. 2009 Jul;37(7 Suppl):S223-6. doi: 10.1097/CCM.0b013e3181aa5c7c.
9
[Therapeutic hypothermia after cardiac arrest saves more lives!].
Tidsskr Nor Laegeforen. 2004 Apr 1;124(7):925-6.
10
Prehospital resuscitated cardiac arrest patients: role for induced hypothermia.
Prehosp Emerg Care. 2009 Jul-Sep;13(3):402-5. doi: 10.1080/10903120902935314.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验