Borna Sedigheh, Borna Hajiehe, Khazardoost Soghra
Department of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, Iran.
Arch Iran Med. 2006 Apr;9(2):115-8.
The aim of this study was to evaluate the outcome of pregnancies in Iranian women with immune thrombocytopenic purpura (ITP).
In a historical cohort study, maternal and neonatal outcomes were studied in 30 pregnant women with ITP at a hospital in Tehran, from January 1994 through November 2003.
Twenty-two cases were diagnosed as ITP before and 8 during pregnancy. Thrombocytopenia (platelet count <150 x 10(9)/L) occurred in 22 pregnancies. Eleven (37%) had vaginal delivery and 19 (63%) underwent elective cesarean section. Eight women had severe postpartum hemorrhage. All live-born neonates were delivered in good condition at term. Neonatal thrombocytopenia occurred in 20 (67%) neonates. No bleeding complications occurred in any of the neonates.
The outcome of pregnancy in pregnant women with ITP is generally good. Cesarean section should only be performed for obstetric indications. Postpartum hemorrhage is common in these women. Postpartum hemorrhage is unrelated to the mode of delivery. Severe thrombocytopenia and bleeding in the offspring are uncommon.
本研究的目的是评估患有免疫性血小板减少性紫癜（ITP）的伊朗女性的妊娠结局。
在一项历史性队列研究中，对1994年1月至2003年11月期间在德黑兰一家医院的30例患有ITP的孕妇的母婴结局进行了研究。
22例在妊娠前被诊断为ITP，8例在妊娠期间被诊断为ITP。22次妊娠出现血小板减少（血小板计数<150×10⁹/L）。11例（37%）经阴道分娩，19例（63%）接受择期剖宫产。8名妇女发生严重产后出血。所有活产新生儿均足月顺利分娩。20例（67%）新生儿出现血小板减少。所有新生儿均未发生出血并发症。
患有ITP的孕妇的妊娠结局总体良好。剖宫产仅应根据产科指征进行。这些妇女产后出血很常见。产后出血与分娩方式无关。后代严重血小板减少和出血并不常见。
