Zorkaltseva I V, Akberdin I R, Kulikova A V, Kniazev S P, Borodin P M, Aksenovich T I
Genetika. 2006 Mar;42(3):427-9.
The pleiotropic effects of mutations resulting in abnormal dentition were analyzed in Kerry Blue Terrier. A decrease in litter size was demonstrated for dogs with dentition anomalies. The mean litter size was 5.72 puppies when both parents had normal dentition and 3.64 puppies when the parents had hypodontia. Analysis showed that the decrease in litter size cannot be fully explained by the effect of inbreeding and is most probably associated with the pleiotropic effect of the genes controlling teeth development on the embryonic viability.
在凯利蓝梗犬中分析了导致牙列异常的突变的多效性作用。结果表明，牙列异常的犬只窝产仔数减少。当双亲牙列正常时，平均窝产仔数为5.72只幼犬；当双亲有牙量减少时，平均窝产仔数为3.64只幼犬。分析表明，窝产仔数的减少不能完全用近亲繁殖的影响来解释，很可能与控制牙齿发育的基因对胚胎活力的多效性作用有关。
