Yoshinaga Harumi, Koutroumanidis Michael, Kobayashi Katsuhiro, Shirasawa Atsushi, Kikumoto Kenichi, Inoue Takushi, Oka Makio, Ohtsuka Yoko
Department of Child Neurology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan.
Epilepsia. 2006 Apr;47(4):781-7. doi: 10.1111/j.1528-1167.2006.00519.x.
Panayiotopoulos syndrome (PS) is a type of benign childhood partial epilepsy that is frequently associated with abundant multifocal spikes other than main occipital spikes on the EEG. In this study, we investigated the characteristic features of dipoles in PS.
We performed dipole analysis of the interictal occipital spike discharges seen in 10 children with PS (group A) and in 10 children with other types of symptomatic localization-related epilepsy (group B). We analyzed the dipoles of the averaged spike in each patient.
In group A, the averaged occipital spikes in each patient showed dense dipole locations in the mesial occipital area; in group B, widely scattered dipole locations were observed. In Group A, the geometric centers of the dipoles at each time point (such as at the main negative peak and before or after the main peak) were estimated in the neighboring locations. In contrast, they tended to be scattered in group B.
Our study reveals that PS has high dipole stability, similar to that of rolandic epilepsy. From the electroencephalographic view, this seems to indicate a close link between these two syndromes.
潘纳约托普洛斯综合征（PS）是一种儿童期良性部分性癫痫，脑电图（EEG）上除主要枕叶棘波外常伴有大量多灶性棘波。在本研究中，我们调查了PS中偶极子的特征。
我们对10例PS患儿（A组）和10例其他类型症状性定位相关癫痫患儿（B组）发作间期枕叶棘波放电进行了偶极子分析。我们分析了每位患者平均棘波的偶极子。
在A组中，每位患者的平均枕叶棘波在枕叶内侧区域显示出密集的偶极子位置；在B组中，观察到偶极子位置广泛分散。在A组中，每个时间点（如主要负峰处以及主峰之前或之后）偶极子的几何中心在相邻位置进行估计。相比之下，它们在B组中倾向于分散。
我们的研究表明，PS具有较高的偶极子稳定性，类似于罗兰多癫痫。从脑电图角度来看，这似乎表明这两种综合征之间存在密切联系。
