Rahman Mokhlasur, Bhuiyan N A, Kuhn I, Ramamurthy T, Rahman M, Mollby R, Nair G Balakrish
Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm, Sweden.
Epidemiol Infect. 2006 Oct;134(5):985-9. doi: 10.1017/S0950268806006017. Epub 2006 Feb 28.
During recent years a pandemic clone of Vibrio parahaemolyticus has emerged. Isolates of this clone are distributed among several serotypes, but are genotypically related. In the present study, a phenotyping method (biochemical fingerprinting) was used to characterize pandemic and non-pandemic isolates belonging to V. parahaemolyticus. It was found that the pandemic isolates showed a high level of phenotypic homogeneity and a majority of the pandemic isolates belonged to the same biochemical phenotype, whereas non-pandemic V. parahemolyticus isolates were more heterogeneous. In conclusion, biochemical fingerprinting of V. parahaemolyticus can be used as a first screening method to differentiate between pandemic and non-pandemic isolates of V. parahaemolyticus.
近年来,出现了一种大流行的副溶血性弧菌克隆株。该克隆株的分离株分布于几种血清型中,但在基因型上相关。在本研究中,采用一种表型分析方法(生化指纹图谱)对属于副溶血性弧菌的大流行株和非大流行株进行特征分析。结果发现,大流行株表现出高度的表型同质性,大多数大流行株属于相同的生化表型,而非大流行的副溶血性弧菌分离株则更加异质。总之,副溶血性弧菌的生化指纹图谱可作为区分副溶血性弧菌大流行株和非大流行株的初步筛选方法。