Shaboltas Alla V, Toussova Olga V, Hoffman Irving F, Heimer Robert, Verevochkin Sergei V, Ryder Robert W, Khoshnood Kaveh, Perdue Tom, Masse Benoit R, Kozlov Andrei P
The Biomedical Center and St. Petersburg State University, 7 Pudozhskaya Street, St. Petersburg, 197110 Russia.
J Acquir Immune Defic Syndr. 2006 Apr 15;41(5):657-63. doi: 10.1097/01.qai.0000220166.56866.22.
In St. Petersburg, Russia, we sought to describe the characteristics of active high-risk injection drug users (IDUs) to evaluate the associations between behavioral and demographic characteristics and HIV-1 infection and to describe 3 discrete recruitment methods.
Active high-risk IDUs were recruited in 3 ways: through street outreach, at facilities serving IDUs, and by network-based chain referral. Recruits were screened, counseled, and tested for HIV-1. Sociodemographic and behavioral data were collected. HIV-1 prevalence was analyzed as a function of sociodemographic and behavioral variables.
During the 10-month recruitment period, data from 900 participants were collected: median age was 24 years, and in the previous month, 96% used heroin and 75% shared needles with others. The baseline HIV prevalence was 30% (95% confidence interval [CI]: 27 to 33). Recruitment through social networks was the most productive strategy. HIV-positive individuals were younger, but none of the other sociodemographic or behavioral characteristics differed significantly by HIV status.
The estimated HIV prevalence of 30% places St. Petersburg among the worst IDU-concentrated epidemics in Europe. Recruitment through network-based chain referral is a useful method for recruiting active IDUs. Sociodemographic and behavioral links to prevalent HIV infection remain to be elucidated.
在俄罗斯圣彼得堡，我们试图描述活跃的高风险注射吸毒者（IDU）的特征，以评估行为和人口统计学特征与HIV-1感染之间的关联，并描述三种不同的招募方法。
通过三种方式招募活跃的高风险IDU：街头外展、在为IDU服务的机构以及基于网络的链式转介。对招募对象进行HIV-1筛查、咨询和检测。收集社会人口统计学和行为数据。分析HIV-1患病率与社会人口统计学和行为变量之间的关系。
在为期10个月的招募期间，收集了900名参与者的数据：中位年龄为24岁，在上个月，96%的人使用海洛因，75%的人与他人共用针头。基线HIV患病率为30%（95%置信区间[CI]：27至33）。通过社交网络招募是最有效的策略。HIV阳性个体更年轻，但其他社会人口统计学或行为特征在HIV状态方面没有显著差异。
估计30%的HIV患病率使圣彼得堡成为欧洲IDU集中流行最严重的地区之一。通过基于网络的链式转介进行招募是招募活跃IDU的一种有用方法。与普遍存在的HIV感染相关的社会人口统计学和行为联系仍有待阐明。
