Khaiutin V M, Sonina R S
Fiziol Zh SSSR Im I M Sechenova. 1991 Jun;77(6):1-11.
The histomechanical hypothesis of working hyperemia in skeletal muscle was verified by comparison of the dynamics and values of frog submaxillary muscle arterioles dilation under: 1) 4-Hz twitch contraction and 2) imitation of mechanical component of the twitch contractions. Deformation of arterioles occurred during incomplete tetanus with the maximal effect at the peaks of twitches. The repetitive displacements of a small bunch of muscle fibers with the frequency of 4 Hz and the amplitude of 0.05 to 0.25 mm caused a dilation of the arterioles attached to the fibers. The outer diameter of the arterioles might increase up to 2.2-2.3-fold, i.e. in the same range as under twitch contractions. The data showed the similarity in latency values, in the dynamics of arteriole dilation, and the dependency of the latter on the phase of the spontaneous vasomotion preceding the compared stimuli. These findings suggest that arteriolar dilation is determined by mechanically induced inactivation of pace-makers of these vessels both during passive deformations and under twitch contractions.
通过比较青蛙下颌下肌小动脉在以下两种情况下扩张的动力学和数值，验证了骨骼肌工作性充血的组织力学假说：1）4赫兹的抽搐收缩；2）模拟抽搐收缩的机械成分。小动脉的变形发生在不完全强直收缩期间，在抽搐峰值时效果最大。一小束肌肉纤维以4赫兹的频率和0.05至0.25毫米的振幅重复位移，导致附着在纤维上的小动脉扩张。小动脉的外径可能会增加到2.2 - 2.3倍，即在与抽搐收缩相同的范围内。数据显示了潜伏期值、小动脉扩张动力学以及后者对比较刺激之前自发血管运动阶段的依赖性方面的相似性。这些发现表明，无论是在被动变形还是抽搐收缩期间，小动脉扩张都是由这些血管的机械诱导起搏器失活所决定的。
