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[家兔肠系膜完整及交感神经切除后微血管对儿茶酚胺反应的特征]

[The characteristics of the reactions of intact and sympathectomized microvessels of the rabbit mesentery to catecholamines].

作者信息

Balashov N V, Dobrynin A A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1991 Jun;77(6):34-41.

PMID:1665817
Abstract

The sensitivity of smooth muscle cells' adrenoreceptors to noradrenaline (NA) and dopamine (DA) was studied in intact and desympathised arterial microvessels of the rabbit mesentery. The arterioles differed from each other in their sensitivity to catecholamines depending on their diameter. However, in conditions of chemical desympathisation, the sensitivity to NA and DA increased in all the microvessels whereas the degree of narrowing of the microvessels' lumen remained practically the same. These findings suggest a heterogeneous character of physiological properties of vascular smooth muscle cells within the arterial part of the microcirculatory module of the rabbit mesentery.

摘要

在兔肠系膜完整和去交感神经的动脉微血管中,研究了平滑肌细胞肾上腺素能受体对去甲肾上腺素(NA)和多巴胺(DA)的敏感性。根据直径不同,小动脉对儿茶酚胺的敏感性也不同。然而,在化学去交感神经的条件下,所有微血管对NA和DA的敏感性均增加,而微血管管腔的狭窄程度实际上保持不变。这些发现表明,兔肠系膜微循环模块动脉部分血管平滑肌细胞的生理特性具有异质性。

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