Horvitz R A, Morgan J P, Fleckenstein L
Ann Intern Med. 1975 May;82(5):601-7. doi: 10.7326/0003-4819-82-5-601.
Brand name and gereric prescriptions for 12 drugs were surveyed at 33 pharmacies in the Rochester, New York, area to determine how frequently generic prescriptions were filled with a product other than the major brand, and at a savings to the consumer. Generic prescriptions for ampicillin, erythromycin, propoxyphene, and dioctyl sodium sulfosuccinate were often filled at prices lower than comparable brand name prescriptions. Occasional, but often substantial, savings were obtained for papaverine, pentaerythritol tetranitrate, and conjugated estrogens. No savings were obtained for penicillin V, chlorpheniramine, diphenylhydantoin, sulfisoxazole, or methenamine mandelate. The pharmacists included in the survey identified correctly a mean of 18.5 out of 22 drugs as to whether products other than the major brand were available. A sample of physicians identified correctly a mean of 14.1 drugs. Pharmacists who were better informed as to which drugs were available generically were more likely to stock alternative products and more likely to charge lower prices on generic prescriptions than on brand name prescriptions.
在纽约罗切斯特地区的33家药店对12种药品的品牌药和仿制药处方进行了调查,以确定仿制药处方用主要品牌以外的产品配药的频率以及为消费者节省的费用。氨苄青霉素、红霉素、丙氧芬和磺琥辛酯钠的仿制药处方配药时,价格通常低于同类品牌药处方。对于罂粟碱、戊四硝酯和结合雌激素,偶尔能节省费用,但数额往往较大。青霉素V、氯苯那敏、苯妥英、磺胺异恶唑或孟德立胺没有节省费用。参与调查的药剂师在22种药品中平均能正确识别出18.5种是否有主要品牌以外的产品。一组医生平均能正确识别出14.1种药品。对于哪些药品有仿制药了解更充分的药剂师,比起品牌药处方,更有可能储备替代产品,也更有可能对仿制药处方收取较低价格。