去铁胺B，一种大肠杆菌运动的抑制剂，可逆转环磷酸腺苷的刺激作用。
Desferrioxamine B, an inhibitor of Escherichia coli motility, reversing the stimulating effect of cyclic adenosine 3',5'-monophosphate.
作者信息
Maruyama H B, Azuma H, Koto Y, Suhara Y
出版信息
Antimicrob Agents Chemother. 1975 Mar;7(3):377-80. doi: 10.1128/AAC.7.3.377.
Abstract
A substance inhibiting Escherichia coli motility was isolated by "motilometry" assay from the culture broth of Streptomyces sp. strain NR9GG8 and was found to be identical with desferrioxamine B. Its inhibitory effect was reversed by cyclic adenosine 3',5'-monophosphate (cAMP), while the motility stimulation by cAMP was diminished by this inhibitor. Its effects on various enzymes involved in cAMP metabolism of function of cAMP were examined.
摘要
通过“运动测定法”从链霉菌属菌株NR9GG8的培养液中分离出一种抑制大肠杆菌运动的物质，发现其与去铁胺B相同。其抑制作用可被环磷酸腺苷（cAMP）逆转，而cAMP对运动的刺激作用则被该抑制剂减弱。研究了其对参与cAMP代谢或cAMP功能的各种酶的影响。
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