Webb John, Chandavimol Mann, Hamburger Jaap N, Pate Gordon, McManus Bruce, Krucoff Mitch, Mancini G B John
Cardiology Department of St. Paul's Hospital, Vancouver, British Columbia, Canada.
J Invasive Cardiol. 2006 May;18(5):188-92.
Intracoronary thrombus is often problematic during percutaneous coronary intervention. Rinspiration is a new thrombectomy catheter system designed to mechanically disrupt and remove intravascular thrombus.
Rinspiration thrombectomy was performed in 15 patients with angiographically visible thrombus in native coronary arteries (10 cases) and in saphenous grafts (5 cases). Indications included acute myocardial infarction in 11 patients and postinfarction ischemia in 4 patients.
The Rinspiration system appeared relatively simple to use. There were no device-related complications. Thrombectomy resulted in an improvement in thrombus grade from 3.8 +/- 1.6 to 2.5 +/- 1.7 (p = 0.02), and TIMI flow from 1.5 +/- 1.3 to 2.2 +/- 1.0 (p = 0.047). Stenting further improved thrombus grade to 0.8 +/- 1.6 and TIMI flow to 2.6 +/- 0.8. At 30-day follow up all patients remained free of repeat revascularization and reinfarction; 1 patient died from hemorrhagic stroke.
The Rinspiration system appears capable of safely removing intracoronary thrombus and warrants further evaluation.
冠状动脉内血栓在经皮冠状动脉介入治疗期间常常成为问题。Rinspiration是一种新的血栓切除术导管系统，旨在机械性地破坏和清除血管内血栓。
对15例患者进行了Rinspiration血栓切除术，这些患者在自身冠状动脉（10例）和隐静脉移植物（5例）中存在血管造影可见的血栓。适应症包括11例急性心肌梗死患者和4例心肌梗死后缺血患者。
Rinspiration系统使用起来相对简单。没有与器械相关的并发症。血栓切除术使血栓分级从3.8±1.6改善至2.5±1.7（p = 0.02），TIMI血流从1.5±1.3改善至2.2±1.0（p = 0.047）。置入支架进一步将血栓分级改善至0.8±1.6，TIMI血流改善至2.6±0.8。在30天随访时，所有患者均未进行再次血管重建和再梗死；1例患者死于出血性卒中。
Rinspiration系统似乎能够安全地清除冠状动脉内血栓，值得进一步评估。
