Suter M, Paroz A, Calmes J-M, Giusti V
Department of Visceral Surgery, Diabetology and Metabolism, Centre Hospitalier Universitaire Vaudois, 1860 Aigle, Lausanne, Switzerland.
Br J Surg. 2006 Jun;93(6):726-32. doi: 10.1002/bjs.5336.
Roux-en-Y gastric bypass (RYGBP) is usually considered as the procedure of choice for morbid obesity, but its use has been limited in Europe. It is not known whether results with European patients match those from the USA.
A total of 466 patients were followed prospectively regarding weight loss, co-morbidities, quality of life and morbidity after primary laparoscopic RYGBP. Overall assessment was done using the bariatric analysis and reporting outcome system (BAROS).
Conversion to open surgery was necessary in three patients. The overall early morbidity rate was 17.0 per cent and the rate of major complications was 4.7 per cent. The mortality rate was 0.2 per cent. Major morbidity decreased over time. Excess weight loss of over 50 per cent was maintained for up to 4 years in 71.4 per cent of the morbidly obese and 65.2 per cent of the super-obese patients. Co-morbidities resolved or improved in most patients and quality of life improved. At 3 years, the BAROS score was excellent or very good in 77.1 per cent and good in 22.8 per cent. Late complications leading to reoperation developed in 19 patients (4.1 per cent).
These results are satisfactory and comparable to those reported from the USA. Owing to limitations associated with purely restrictive bariatric procedures, laparoscopic RYGBP is likely to become the procedure of choice for treatment of morbid obesity in Europe.
Roux-en-Y胃旁路术(RYGBP)通常被视为治疗病态肥胖的首选术式,但在欧洲其应用一直受限。目前尚不清楚欧洲患者的手术效果是否与美国患者的一致。
对466例行初次腹腔镜RYGBP手术的患者进行前瞻性随访,观察其体重减轻情况、合并症、生活质量及发病率。采用肥胖症分析与报告结果系统(BAROS)进行总体评估。
3例患者需转为开腹手术。总体早期发病率为17.0%,主要并发症发生率为4.7%。死亡率为0.2%。主要发病率随时间下降。71.4%的病态肥胖患者和65.2%的超级肥胖患者体重减轻超过50%的情况维持了长达4年。大多数患者的合并症得到缓解或改善,生活质量提高。3年时,77.1%的患者BAROS评分优秀或非常好,22.8%的患者评分良好。19例患者(4.1%)出现导致再次手术的晚期并发症。
这些结果令人满意,与美国报告的结果相当。由于单纯限制性减肥手术存在局限性,腹腔镜RYGBP可能会成为欧洲治疗病态肥胖的首选术式。